نتایج جستجو برای: endocrine disruptor chemicals

تعداد نتایج: 87723  

2017
Josh Bloom

A strange but interesting paper [2] by scientists at The University of Wisconsin, which just appeared in PNAS, examines whether two similar sunscreen chemicals, homosalate and octisalate, could be a possible treatment for multiple sclerosis (MS). (See my colleague Julianna LeMieux's companion article "Sunscreen, MS And A Scientific Finding That Is Hard To Believe [3]" about the biological activ...

Journal: :Environmental science and pollution research international 2010
Eric B Higley John L Newsted Xiaowei Zhang John P Giesy Markus Hecker

BACKGROUND, AIM, AND SCOPE In response to concerns about chemical substances that can alter the function of endocrine systems and may result in adverse effects on human and ecosystem health, a number of in vitro tests have been developed to identify and assess the endocrine disrupting potential of chemicals and environmental samples. One endpoint that is frequently used in in vitro models for t...

Journal: :Science of The Total Environment 2021

Endocrine-disrupting chemicals have the ability to interfere with and alter functions of hormone system, leading adverse effects on reproduction, growth development. Despite growing concerns over their now ubiquitous presence in environment, endocrine-related human health remain largely outside comparative toxicity characterization frameworks as applied for example life cycle impact assessments...

2016
Huixiao Hong Jie Shen Hui Wen Ng Sugunadevi Sakkiah Hao Ye Weigong Ge Ping Gong Wenming Xiao Weida Tong

Endocrine disruptors such as polychlorinated biphenyls (PCBs), diethylstilbestrol (DES) and dichlorodiphenyltrichloroethane (DDT) are agents that interfere with the endocrine system and cause adverse health effects. Huge public health concern about endocrine disruptors has arisen. One of the mechanisms of endocrine disruption is through binding of endocrine disruptors with the hormone receptors...

2011
L. C. Guidice P. A. Hunt C. Leranth J. P. Myers A. Nadal N. Olea V. Padmanabhan C. S. Rosenfeld A. Schneyer G. Schoenfelder C. Sonnenschein R. W. Stahlhut S. H. Swan H. S. Wang C. S. Watson

The idea that xenobiotic chemicals could inappropriately modlate the endocrine system thereby causing detrimental effects n wildlife and humans was first proposed 20 years ago at the atershed Wingspread Conference [1,2]. These endocrine disruptng chemicals (EDCs) have long been controversial, with a great eal of discussion raging in the scientific literature. Much of this ontroversy has centere...

Journal: :Environmental Health 2005
Jason M Vogel

The Endocrine Disruptor Screening Program (EDSP), mandated by the United States Congress in the Food Quality Protection Act of 1996, attempts to protect public health from adverse endocrine effects of synthetic chemical compounds by establishing a new testing regime. But the complexities and uncertainties of endocrine disruption and its broader regulatory and social context all but ensure the f...

Journal: :Endocrinology 2015
Shane M Regnier Andrew G Kirkley Honggang Ye Essam El-Hashani Xiaojie Zhang Brian A Neel Wakanene Kamau Celeste C Thomas Ayanna K Williams Emily T Hayes Nicole L Massad Daniel N Johnson Lei Huang Chunling Zhang Robert M Sargis

Environmental endocrine disruptors are implicated as putative contributors to the burgeoning metabolic disease epidemic. Tolylfluanid (TF) is a commonly detected fungicide in Europe, and previous in vitro and ex vivo work has identified it as a potent endocrine disruptor with the capacity to promote adipocyte differentiation and induce adipocytic insulin resistance, effects likely resulting fro...

Journal: :Environmental Health Perspectives 1999
B A Schwetz

'We, as a scienti/ic cornznity, s.hon/ld responsibly addrdess new scientific issutes by zeroing i ni on the highest priority needs with strategies that are in proportioni to the size oJthe problens. Committing resources to one project often means another issue will go unattended. The potential impact on human health and environmental quality can be significant. Admittedly, research career goals...

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