Paraquat, a widely used herbicide, was found to cause a marked stimulation of lipid peroxidation in the human placental microsomes in vitro. Both NADPH and chelated iron were necessary to observe paraquat-stimulated lipid peroxidation. The malondialdehyde accumulation in the incubation medium increased with increase in time, protein and paraquat concentration. The reaction did not exhibit the i...

Free radicals are normally produced by living organism, at controlled production rate they perform physiological functions as signal transduction molecules. However, situations leading to an overproduction that surpasses antioxidant capacity creates oxidative stress. Consequently, damage to the cell membrane, protein, DNA and cell death are observed. Dairy cattle are susceptible to oxidative st...

Oxidative stress has been suggested to contribute to the pathophysiology of schizophrenia. Increased oxidative stress is the result of either an increased production of free radicals or a depletion of the endogenous antioxidants. However, whether this imbalance of oxidant-antioxidant status in schizophrenia is integral to disease itself or the effect of antipsychotic drugs is not clearly unders...

Aniline is widely used chemical for industrial purpose. Exposure to aniline can lead various health issues in human being. The most common toxic effect of splenotoxicity which produced via the generation oxidative stress. present study examines protective coenzyme Q10 and N-acetyl cysteine on spleen weight, body endogenous antioxidants membrane bound ATPases hydrochloride (AH) induced toxicity ...

AOCS Official Method Ce 6-86 "Antioxidants, Liquid Chromatographic Method" was originally developed to confirm the correct antioxidant was added at the specified concentration to refined oils. Today, this method is increasingly utilized to validate that antioxidants are absent from oil products. False positive results can have a significant impact on the ability to sell products in specific mar...

The increasing susceptibility of broiler chickens to ascites syndrome has coincided with a continuing genetic and nutritional improvement in their feed efficiency and growth rate. Ascites is multifactorial and interactions between environmental and endogenous factors play a particularly important role. The selection of fast growing broilers for high feed efficiency, which is characterized by hy...