BACKGROUND AND PURPOSE Infections are common after stroke and associated with worse outcome. Clinical trials evaluating the benefit of prophylactic antibiotics have produced mixed results. This study explores the possibility that antibiotics of different classes may differentially affect stroke outcome. METHODS Lewis rats were subjected to transient cerebral ischemia (2 hours) and survived fo...

Orbifloxacin is a fluoroquinolone drug used widely in companion animal medicine. In this study, we firstly determined post-antibiotic effects (PAEs) and post-antibiotic sub-minimum inhibitory concentrations (MIC) effects (PA-SMEs) of orbifloxacin for two strains each of Escherichia coli and Pseudomonas aeruginosa from dogs, and these parameters were compared with those of enrofloxacin. At twice...

BACKGROUND Uncomplicated urinary tract infections (UTI) in dogs usually are treated with antimicrobial drugs for 10-14 days. Shorter duration antimicrobial regimens have been evaluated in human patients. HYPOTHESIS A high dose short duration (HDSD) enrofloxacin protocol administered to dogs with uncomplicated UTI will not be inferior to a 14-day treatment regimen with amoxicillin-clavulanic a...

The occurrence of fluoroquinolone antibiotics in wastewater has drawn great attention. Adsorption of widely used fluoroquinolone antibiotics (enrofloxacin and ofloxacin) in wastewater using bamboo biochar was investigated. More than 99% of fluoroquinolone antibiotics were removed from the synthetic wastewater through adsorption. Adsorption capacities of bamboo biochar slightly changed when pH i...

The in vitro activities of several cephalosporins and quinolones against 195 strains of Escherichia coli isolated from diary calves affected by neonatal diarrhea were determined. One hundred thirty-seven of these strains produced one or more potential virulence factors (F5, F41, F17, cytotoxic necrotizing factor, verotoxin, and the eae gene), but the remaining 58 strains did not produce any of ...

A major risk for astronauts during prolonged space flight is infection as a result of the combined effects of microgravity, situational and confinement stress, alterations in food intake, altered circadian rhythm, and radiation that can significantly impair the immune system and the body's defense systems. We previously reported a massive increase in morbidity with a decrease in the ability to ...

A total of 159 Thai isolates of Mycoplasma hyopneumoniae isolated from pneumonic lungs of pigs during 2006-2011 were investigated for their in vitro susceptibility to 12 antimicrobial agents. Low activity of chlortetracycline was indicated by the MIC range from 3.12-100 μg/ml and MIC90 of 50 μg/ml. Seventy-six isolates showed resistance to enrofloxacin, whereas 2 isolates showed resistance to m...

We assessed the in vitro activity of selected antimicrobial agents against 95 Staphylococcus aureus strains causing both clinical and subclinical bovine mastitis belonging to 61 dairy farms from the Central dairy area of Argentina. Minimal inhibitory concentrations (MICs) of penicillin, oxacillin, gentamicin, erythromycin, enrofloxacin and florfenicol were estimated. In addition, the agar diffu...

The in vitro activities of aivlosin tylosin tiamulin, erythromycin, oxytetracycline, spectinomycin, lincomycin, lincomycin-spectinomycin (1:2) and enrofloxacin were determined against twenty-eight isolates of Mycoplasma gallisepticum and 4 isolates of Mycoplasma synoviae using microbroth dilution method. The isolates showed various susceptibilities to antimicrobial agents. Aivlosin, lincomycin-...

Background & Aims: Most antibiotics not only inhibit microbial growth, but also can increase the growth of livestock. Although enrofloxacin is one of the most commonly used antibiotics, it has high toxicity on the kidney, liver, and brain. The aim of this study was to synthesize nanocellulose conjugated with aminobenzyl purin and to study its enrofloxacin adsorption capability. Methods: Nan...