We describe 3 siblings who suffered from marked eosinophilia with organ involvement. One sibling, who experienced cervical lymphadenopathy and peripheral neuropathy with eosinophilia (5,834 cells/μL) following bronchial asthma, was diagnosed with Churg-Strauss syndrome (CSS) according to the criteria of the American College of Rheumatology. Another sibling, who suffered from severe asthma with ...

BACKGROUND Eosinophilia is frequently associated with peripheral neuropathy, and neuropathic pain is a major presentation. Little is known about the involvement of sensory nerve terminals and the vasculature in the skin of patients with eosinophilia. OBJECTIVES To investigate the skin innervation and the pathological abnormalities of the cutaneous vasculature and their clinical significance i...

Greval (1940) reported that some cases of ' Eosinophilia ' give false positive Wassermann reaction. More recently Menon (1945) and D'Abrera and Stork (1946) reported similar reactions in tropical eosinophilia. It was proposed to record results of Wassermann reaction and Kahn test in all cases of eosinophilia as a part of the investigation into the incidence of false positive serologic reactions...

A sputum eosinophilia is observed in 10-40% of COPD subjects. The blood eosinophil count is a biomarker of sputum eosinophilia, but whether it is associated with bronchial submucosal eosinophils is unclear. In 20 COPD subjects and 21 controls we assessed the number of bronchial submucosal eosinophils and reticular basement membrane thickening and found these were positively correlated with the ...

A 73 yr old man with a marked eosinophilia, associated with generalized bronchial carcinoma was observed. Ten months earlier his blood count was normal. The mechanism of the eosinophilia is discussed.

Immigrants from undeveloped countries are a growing problem in Europe. Spain has become a frequent destination for immigrants (20% of whom are children) because of its geographic location and its historic and cultural links with Africa and Latin America. Eosinophilia is frequent in adult immigrants, travelers and expatriates coming from tropical areas. However, there are few studies that focus ...

Frimodt-Moller and Barton (1940) described a clinical condition characterized by leukocytosis and eosinophilia and associated with cough, fever, loss of weight and strength, bloodstained sputum or frank haemoptysis and asthma or bronchitis in varying combinations and degrees. These cases gave an x-ray picture of the chest closely resembling that of miliary tuberculosis. The common pattern of si...