Phylogenetic analysis may serve as a valuable tool in assessing the epidemiological relation between viral DNA sequences. In order to increase the likelihood of observing phylogenetic separation of sequences as well as to give strong forensic evidence regarding transmission, phylogenetic analysis needs to be performed on appropriate local control sequences and by sequencing of at least two gene...

conclusions the highest frequency of fc was seen in younger than 20-month-old children. except for the lower incidence of positive history of prematurity and higher prevalence of gastroenteritis, results of the present study are relatively similar to other studies. patients and methods in this cross-sectional study, the patients with diagnosis of febrile seizure were the target population. we o...

background: on tuberculosis control standpoint, the treatment of children with tb is not considered a priority as they rarely transmit the disease and contribute little to the maintenance of the tuberculosis epidemic. therefor this study conducted to describe pediatric tb cases, and to identify pattern of risk factors in non-endemic communities materials and methods: the present cross- sectiona...

BACKGROUND To our knowledge, no study has assessed the validity of family history data provided by probands with adult-onset dystonia. OBJECTIVE To measure the sensitivity and specificity of interviewing patients with primary adult-onset dystonia as a method for obtaining information on dystonia in first-degree relatives. PARTICIPANTS Seventy probands with primary adult-onset dystonia were ...

BACKGROUND The aim was to compare tuberculosis trends in Mexico and United States and to evaluate Mexican diagnostic methods and contact investigation. METHODS Retrospective comparative study of tuberculosis cases and incidence rates between both countries (1990-2010). Diagnostic methods and contact investigations were also evaluated for Mexico. Estimates were obtained from official websites....

Twin and family studies have shown that most traits are at least moderately heritable. But what are the implications of finding genetic influence for the design of intervention and prevention programs? For complex traits, heritability does not mean immutability, and research has shown that genetic influences can change with age, context, and in response to behavioral and drug interventions. The...

BACKGROUND Mycobacterium tuberculosis is characterised by limited genomic diversity, which makes the application of whole genome sequencing particularly attractive for clinical and epidemiological investigation. However, in order to confidently infer transmission events, an accurate knowledge of the rate of change in the genome over relevant timescales is required. METHODS We attempted to est...

BACKGROUND Food safety issues are not a new issue in science, but due to the dynamic changes in the modern world it is as equally important as decades ago. The aim of the study was to address the efforts in the development of a comprehensive food safety system in Serbia, and make specific recommendations regarding the improvement of epidemiological investigation capacity as a useful tool which ...