The objective of this article is to review the dramatic changes that have occurred in the field of epilepsy surgery since the founding of Epilepsy Action in 1950. We have chosen to consider these advances from the biomedical perspective (the physician and basic scientist), and the behavioral perspective (the psychologist and the patient). Both these viewpoints are equally important in understan...

Abstract Objective To select patients with drug resistant epilepsy following up in Pediatrics Neurology Outpatient Clinic of Children's Hospital, Ain Shams University who are candidates for surgery and to detect outcome such children as regards seizures control. Methods This prospective study was conducted over a period 36 months comprises 3 stages. Stage 1 includes selection preoperative evalu...

Frontal lobe epilepsy accounts for only 10-20% of the patients in surgical series, but the incidence in non-surgical patient cohorts seems to be much higher. The typical clinical presentation of the seizures includes contralateral clonic movements, uni- or bilateral tonic motor activity as well as complex automatism. The yield of surface EEG may be limited due to the difficulty in detection of ...

PURPOSE Cerebral cavernous malformations (CCMs) are frequently associated with intractable epilepsy. Whereas surgery indication in single CCMs is clear, data regarding the efficacy of epilepsy surgery in patients with multiple CCMs are scarce. We sought to clarify diagnostic requirements and postoperative outcome in patients with multiple CCMs and refractory epilepsy. METHODS Retrospective an...

Invasive surgery may be required to resect the area of seizure in approximately one third epilepsy patients. A combination diagnostic tests is used ascertain resection area, including nuclear imaging (PET/SPECT) techniques

The occurrence of de novo psychogenic seizures after epilepsy surgery is rare, and is estimated in 1.8% to 3.6%. Seizures after epilepsy surgery should be carefully evaluated, and de novo psychogenic seizures should be considered especially when there is a change in the ictal semiology. We report a patient with de novo psychogenic seizures after anterior temporal lobe removal for refractory tem...

Mirror focus is one of the evidence of progression in epilepsy, and also has practical points for curative resective epilepsy surgery. The mirror foci are related to the kindling phenomena that occur through interhemispheric callosal or commissural connections. A mirror focus means the secondary epileptogenic foci develop in the contralateral hemispheric homotopic area. Thus mirror foci are mos...

http://dx.doi.org/10.1016/j.seizure.2016.06.017 1059-1311/Crown Copyright 2016 Published by Elsevier Ltd on behalf of Briti The relationship between epilepsy and psychosis has been recognised since the mid-nineteenth century. For pragmatic reasons, psychotic symptoms are always grouped according to their temporal relationship to seizures: ictal, peri/para-ictal and interictal psychoses (IIP). P...

PURPOSE The selection of ideal candidates for extratemporal resective epilepsy surgery is a challenge in resource-poor countries because of the limited presurgical diagnostic facilities and their affordability. To audit the presurgical evaluation strategy and selection for extratemporal resective epilepsy surgery in a resource-poor region. METHODS From the prospective database maintained at a...

Resective epilepsy surgery is an elective therapy indicated in focal epilepsy patients who are resistant to pharmacotherapy. Every effort should be undertaken to perform the procedures as safe and less traumatic as possible. Neuronavigation could represent a suitable tool to reduce surgical morbidity and increase surgical radicality. Here, we present a series of 41 patients who were operated on...