The collagen produced by differentiated cells cultured from human amniotic fluid was characterized in two ways. By chain composition and by 4-hydroxyproline:3-hydroxyproline isomer ratio, the collagen synthesized by F-type (fibroblast) cells was indistinguishable from that made by cultured fetal dermal fibroblasts. The predominant cells in young amniotic fluid cultures, termed AF-type, produced...

compounds were /V-acetylcysteine, bismuththiol. calcium glucarate, (±) catechin, diallyl disulfide, glycaric acid, i>-glucaro-l,4-lactone. \-(4hydro\yphenyl)retinamide, n-limonene, mesna, retinole acid, rutin, quercetin, silymarin, and taurine. In examining the nature of compounds that inhibited rat trachea! epithelial cell transformation, several possible chemoprevcntivc mechanisms appeared t...

The aim of this work was to study the effects of sub-lethal exposure of lead acetate on the histopathology of the gills, liver, kidney and muscle and its accumulation in these organs of Clarias gariepinus. Results showed that lead accumulation in the tissues of C. gariepinus was dependent on the exposure period and lead concentration. Gills and liver were the predominant storage tissue and the ...

On a worldwide perspective chronic liver diseases (CLDs) are very common pathologic conditions which are characterized by reiteration of hepatocyte injury that is mainly induced by chronic infection by hepatitis B and C viruses (HBV and HCV), autoimmune injury and metabolic and/or toxic/drug – induced causes, with chronic alcohol consumption being predominant particularly in western countries. ...

Epithelial tissues function to protect the organism from physical, chemical, and microbial damage and are essential for survival. To perform this role, epithelial keratinocytes undergo a well-defined differentiation program that results in the expression of structural proteins which maintain the integrity of epithelial tissues and function as a protective barrier. This review focuses on structu...

Expression of MHC class II genes by epithelial cells is induced in inflammatory conditions such as autoimmunity and organ transplantation. Class II ligands generated by the epithelial cell processing mechanisms are unknown, although some unique epitopes have been described in epithelial cells that B cells could not generate. Epithelial cells are the targets of autoreactive T cell responses in a...

amniotic epithelial cells (aecs) possess unique characteristics, which make them a suitable source for cell-based therapeutic strategies. aecs have stem cell properties with low-immunogenicity (due to expressing hla-g molecule and absence of mhc class i and ii antigens) and no ethical problems, as well as availability in sufficient numbers, which can be obtained from a placenta. we have recentl...

PURPOSE Wilms' tumors (WTs) exhibit more than one pattern of differentiation, each of which is associated with distinctive clinical features and treatment responses. Mutations in the WT1 gene are found predominantly in WTs with stromal histology. To better understand the biological and clinical features in different WTs, we have analyzed WTs with and without WT1 mutations for a set of parameter...

Isolated frog skin epithelia undergo marked, but reversible swelling when the external skin surface is bathed with conventional NaCl Ringer's and the internal surface with KCl Ringer's solutions. In 2 hours, epithelial thickness increased by over twofold. When NaCl Ringer's was replaced on both sides of the skin, volume returned to control levels in less than 1 hour. When sulfate, rather than c...

Calcifying epithelial odontogenic tumor (CEOT) is a rare benign odontogenic tumor. Here we report 3 cases of CEOT. All patients were women and the age of the patients ranged from 39-48 years. All cases were located in the maxilla. Histologically, one case was epithelial-predominant and consisted of large irregular cribriform sheets of polygonal epithelial cells, dense eosinophilic amyloid-like ...