نتایج جستجو برای: epiya
تعداد نتایج: 116 فیلتر نتایج به سال:
Helicobacter pylori genetic variation is a crucial component of colonization and persistence within the inhospitable niche of the gastric mucosa. As such, numerous H. pylori genes have been shown to vary in terms of presence and genomic location within this pathogen. Among the variable factors, the Bab family of outer membrane proteins (OMPs) has been shown to differ within subsets of strains. ...
BACKGROUND Helicobacter pylori is a vertically inherited gut commensal that is carcinogenic if it possesses the cag pathogenicity island (cag PaI); infection with H.pylori is the major risk factor for gastric cancer, the second leading cause of death from cancer worldwide (WHO). The cag PaI locus encodes the cagA gene, whose protein product is injected into stomach epithelial cells via a Type I...
802 INTRODUCTION Helicobacter pylori is a pathogenic Gram-negative bacterium that colonizes over 50% of the world’s human population. Colonization with H. pylori is linked to numerous gastric disorders including gastritis, peptic ulcer disease and gastric adenocarcinoma (Blaser and Atherton, 2004). Although gastric cancer occurs in fewer than 1% of people colonized by H. pylori (Amieva and El-O...
I n The Curious Case of Benjamin Button, an original short story authored by F. Scott Fitzgerald, the main character ages in reverse, beginning life as a mature adult (i.e., welldifferentiated state) and then progressing inexorably toward a childlike existence (i.e., progenitor state). A molecular counterpart to this process, which frequently occurs during oncogenesis, is transdifferentiation, ...
We refer to the recent publication by Nakano and co-workers in Disease Models & Mechanisms (Nakano et al., 2016). This report claims that the Helicobacter pylori vacuolating cytotoxin (VacA) is the crucial factor inducing the activation of the host cell kinase for translocated CagA, Src, via a mechanism involving the receptor phosphatase RPTP-α using the human duodenum carcinoma cell line AZ-52...
We refer to the recent publication by Nakano and co-workers in Disease Models & Mechanisms (Nakano et al., 2016). This report claims that the Helicobacter pylori vacuolating cytotoxin (VacA) is the crucial factor inducing the activation of the host cell kinase for translocated CagA, Src, via a mechanism involving the receptor phosphatase RPTP-α using the human duodenum carcinoma cell line AZ-52...
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