ERB(Earth Radiation Budget) data describe how the earth gains en-gergy, due to absorbed solar radiation ux, or looses energy, due to emitted thermal radiation ux. Since the atmospheric energetics is described by diierential equations with derivatives in space and in time, high resolution spatial and temporal ERB data should be available. ERB data derived from satellite measurements exist (ERBE(...

Accumulating evidence suggests that ubiquitin E3 ligases are involved in cancer development as their mutations correlate with genomic instability and genetic susceptibility to cancer. Despite significant findings of cancer-driving mutations in the BRCA1 gene, estrogen receptor (ER)-positive breast cancers progress upon treatment with DNA damaging-cytotoxic therapies. In order to understand the ...

The role of estrogen in inducing chemoresistance is not yet fully understood. The objective of this study was to observe the relationship between estrogen levels and cellular response to chemotherapeutic drugs in non-small cell lung cancer (NSCLC) and to reveal the potential mechanisms involved. Cell viability was analyzed after pre-treating NSCLC cells with different levels of estrogen (E2), f...

Use of a bilinear conformal map to achieve a frequency warping nearly identical to that of the Bark frequency scale is described. Because the map takes the unit circle to itself, its form is that of the transfer function of a first-order allpass filter. Since it is a first-order map, it preserves the model order of rational systems, making it a valuable frequency warping technique for use in au...

background hepatocellular carcinoma (hcc) is the fifth most common fatal cancer and an important healthcare problem worldwide. there are many studies describing the prognostic and predictive effects of epidermal growth factor receptor 2 (c-erb-b2) and epidermal growth factor receptor 1 (egfr), transmembrane tyrosine kinases that influence cell growth and proliferation in many tumors. objectives...

4-Methylbenzylidene-camphor (4-MBC) is an organic sunscreen that protects against UV radiation and may therefore help in the prevention of skin cancer. Recent results on the estrogenicity of 4-MBC have raised concerns about a potential of 4-MBC to act as an endocrine disruptor. Here, we investigated the direct interaction of 4-MBC with estrogen receptor (ER) a and ERb in a series of studies inc...

BACKGROUND The authors conducted this prospective study to analyze the amount of interfractional prostate bed motion (PBM) and quantify its components with the use of an endorectal balloon (ERB). METHODS A total of 1,348 cone beam computed tomography images from 46 patients who underwent postprostatectomy radiotherapy were analyzed. For the pilot image, electronic portal imaging, guided by sk...

2,3,7,8,-Tetrachlorodibenzo-p-dioxin (TCDD) administered in vivo causes drastic reduction in the weight of the mouse thymus at low doses (e.g., 30 micrograms/kg single i.p. injection), the reduction becoming statistically significant after 2 days. To understand the cause for such thymic involution TCDD-evoked changes in various biochemical parameters in this tissue were examined. The most notic...

A neu/erb B2 ligand growth factor (NEL-GF) was purified to homogeneity from bovine kidney by a procedure involving ammonium sulfate fractionation (35-70% saturation) followed by sequential column chromatography on DEAE-cellulose (DE52), Sulfadex (sulfated Sephadex G-50), heparin-Sepharose 4B, and Superdex 75 (fast protein liquid chromatography). NEL-GF was found to be a 25-kDa polypeptide accor...