Anorectal malformation is a congenital anomaly and can be either isolated or associated. This often combined with other defects, in particular VACTERL-association (anomalies of the spine, anal region, heart, trachea, esophagus, kidneys extremities), which requires comprehensive diagnosis these patients. Congenital malformations gastrointestinal tract except for esophageal atresia are rare. The ...

 Abstract Background: Esophageal replacement is indicated in certain circumstances including long gap esophageal atresia, severe strictures due to gastro-esophageal reflux (GER) and caustic burns. We analyzed our results of 18 patients who underwent esophageal replacement in our university hospital. Methods: We reviewed esophageal replacements carried out in our department between June 1996 and...

objectives: bloating is a common and bothersome gastrointestinal symptom. despite its high prevalence, associated costs, and effects on the quality of life, very few studies have reported the epidemiology of bloating in iran. through this systematic review, findings and limitations of the current research will be discussed. methods: in march 2012, we searched pubmed, google scholar, scientific ...

â  background hirschsprung’s disease (hd) is a congenital disease in which intesâ­tinal ganglionic cells are absent, leading to intestinal obstruction. the disease has various clinical manifestations and different lengths of bowel may be involved. our aim was to study hirschsprung’s clinical presentations and its rate of intestinal involvement in hospitalized patients in a six year course s...

The maximum volume of air tolerated within a rectal balloon was less in colitic patients than in normal subjects (p < 0 001). Smaller volumes were tolerated by patients with a spontaneously bleeding mucosa than by those with less severe inflammation (p <0 001). Severe urgency of defaecation with incontinence was experienced by about half those with spontaneous mucosal haemorrhage butwas infrequ...

Distension of the rumen limits feed intake by livestock. Ruminal dysfunctions due to bloat, which causes distension by accumulation of excessive gas within the rumen, also reduce feeding. We hypothesized that excessive levels of rumen distension cause feed aversions and that preference increases for feeds eaten in association with recovery from bloat. To test these hypotheses, we determined whe...

The aim of this study was to test the hypothesis that gastric distension can enhance the effect of cholecystokinin (CCK) on reduction of food intake in men and women. Eight normal-weight subjects of each gender were tested four times each with either CCK or saline infusion crossed with gastric distension or no distension. Intravenous infusion of a low dose of CCK octapeptide (CCK-8; 112 ng/min ...

Background: Patients with abdominal bloating and distension exhibit impaired transit of intestinal gas which may lead to excessive gas retention and symptoms. Furthermore, we have previously shown that intestinal gas transit is normally accelerated by rectal distension. We hypothesise that in patients with functional bloating this modulatory mechanism fails and impairs gas transit. Methods: In ...

In spite of voluminous literature that has been written on defecation, the exact mechanism has not yet been fully cleared up. The current study investigated the effect of sigmoid colon (SC) distension on anal motile activity and of anal distension on SC motility. Sixteen healthy volunteers (age 36.2 +/- 11.6 SD years, 10 men) were studied. The SC was distended by a balloon in 10 ml increments o...