نتایج جستجو برای: estrogen receptor α

تعداد نتایج: 754695  

2010
Salehi Niya

steoporosis is a common disease in which the bones become prone to fracture as a result of loss of bone mineral density (BMD). The estrogen receptor (ER) gene is a candidate gene for osteoporosis. This study assesses the relation between estrogen receptor-α gene polymorphism and osteoporosis in a population of Iranian women. Materials & Methods: In the present study, we investigated 200 preand/...

2009
Maria G. Raso Carmen Behrens Matthew H. Herynk Suyu Liu Ludmila Prudkin Natalie C. Ozburn Denise M. Woods Ximing Tang Reza J. Mehran Cesar Moran J. Jack Lee Ignacio I. Wistuba

Purpose: To determine the frequency of estrogen receptor α and β and progesterone receptor protein immunohistochemical expression in a large set of non–small cell lungcarcinoma (NSCLC) specimens and to compare our results with those for some of the same antibodies that have provided inconsistent results in previously published reports. Experimental Design: Using multiple antibodies, we investig...

2016
Jia Min Zhong Weitian Cai Peng Peng Yan Zhang Bo Wang Yan Bai Yun Wang Xukai

BACKGROUND Hyperinsulinemia and insulin resistance have been recently recognized as an important cause of atherosclerosis. Clinical studies have also found that expression of the estrogen receptor is closely related to the incidence of atherosclerosis. This study investigate the effects of insulin and estrogen receptor α (ER-α) in atherosclerosis. METHODS Double knockout ApoE/Lepr mice were g...

Journal: :medical journal of islamic republic of iran 0
mohammad hashemi dept. of clinical biochemistry, zahedan medical university, zahedan , iran . fatemeh karami tehrani cancer research lab, dept. of clinical biochemistry, school of medical sciences, tarbiat modarres university, tehran, iran. saeid ghavami dept. of clinical biochemistry, school of medicine, zahedan medical university, zahedan, iran, majid sirati sabet dept. of clinical biochemistry, school of medicine, qazvin medicaluniversity, qazvin, iran.

abstract background: the aims of this study were to assay the activity of adenosine deaminase (ada) in estrogen receptor positive (mcf-7) and negative (mda-mb468) breast cancer cell lines. methods: mda-mb468 and mcf-7 breast cancer cell lines were cultured in complete medium, striped serum with and without 0.0 1~-lm diethylstilbestrol (des), complete medium in the presence and absence of 111m t...

Journal: :Acta medica Iranica 2016
Hamid Sohanaki Tourandokht Baluchnejadmojarad Farnaz Nikbakht Mehrdad Roghani

Alzheimer's disease (AD) is a disorder with multiple pathophysiological causes, destructive outcomes, and no available definitive cure. Pelargonidin (Pel), an anthocyanin derivative, is an estrogen receptor agonist with little estrogen side effects. This study was designed to assess Pel memory enhancing effects on the a rat Amyloid Beta25-35 (Aβ) intrahippocampal microinjections model of AD in ...

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