The growing number of individuals affected by dementia will intensify the ethical issues that emerge in clinical practice and research, issues early in disease relate to genetic testing, use of medications in mildly affected persons, and diagnostic disclosure. Research issues relate to appropriate informed consent processes, conflict of interests, and research design issues, such as the use of ...

Outlined the issues in informed consent, as well as goals for involving children and adolescents in decisions regarding their own medical treatment. This paper reviews the developmental and clinical considerations, and provides recommendations, for determining particular children's level of involvement. Finally, there are distinct roles for pediatric psychologists in this process, which are des...

— Cybersecurity research demands extensive experimentation to be validated. This experimentation is inherently risky: it may involve any combination of live malicious code, disruptive actions and connectivity to the active Internet. Previously, risky experiments were heavily contained to reduce danger to the experimental infrastructure and the Internet. We argue that such an approach unnecessar...

Dependence on intuitive and experiences would add more complexity in the design process. Novice designers would follow the design of any existing systems without direction. This paper proposed a systematic design approach that provides guidance for novice designers in achieving the targeted usability goal using patterns, and evaluating the prototypes in achieving the determined usability goals....

P. M. Haygarth,1* G. S. Bilotta,1,2 R. Bol,1 R. E. Brazier,2 P. J. Butler,1 J. Freer,3 L. J. Gimbert,4 S. J. Granger,1 T. Krueger,3 C. J. A. Macleod,1 P. Naden,5 G. Old,5 J. N. Quinton,3 B. Smith5 and P. Worsfold4 1 Cross Institute Programme for Sustainable Soil Function (SoilCIP), Institute of Grassland and Environmental Research (IGER), North Wyke Research Station, Okehampton, Devon, EX20 2SB...

In the United Kingdom the Human Fertilisation and Embryology Authority (HFEA) has statutory responsibility for regulating practice in the areas of assisted procreation and research on human embryos. As such it has an almost unique responsibility in the United Kingdom for ethical review of both clinical research and practice in a given field. It is therefore interesting to ask whether it has a u...

M. A. Sutton, E. Nemitz, C. Milford, C. Campbell, J. W. Erisman, A. Hensen, P. Cellier, M. David, B. Loubet, E. Personne, J. K. Schjoerring, M. Mattsson, J. R. Dorsey, M. W. Gallagher, L. Horvath, T. Weidinger, R. Meszaros, U. Dämmgen, A. Neftel, B. Herrmann, B. E. Lehman***†, C. Flechard, and J. Burkhardt Centre for Ecology and Hydrology (Edinburgh Research Station) (CEH), Bush Estate, Penicui...

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BACKGROUND Commentators have expressed concern regarding the existence of proper ethics review systems in developing countries. Our aim is to explore the extent with which investigators from countries in the Eastern Mediterranean (EM) Region consider several ethical practices in the conduct of their research. METHODOLOGY/PRINCIPAL FINDINGS Investigators from 12 countries in the EM region subm...

PURPOSE Independent ethical review committees safeguard participants in human research. The purpose of this study was to describe the current ethical guidelines for human research requirements in the Instructions to Authors of the English language medical journals previously studied in 1995. METHODS The instructions to authors of English language medicine journals from the Abridged Index Medi...