BACKGROUND Heart failure (HF) is a serious complication of acute myocardial infarction (AMI). We explored the excess mortality associated with HF as an early or late complication of AMI and describe changes over time in such excess mortality. METHODS AND RESULTS All patients hospitalized with an incident AMI and without history of prior HF hospitalization were followed up to 1 year after AMI ...

AIMS Define the impact of age at diagnosis on degenerative mitral regurgitation (MR) prognosis. METHODS AND RESULTS The Mitral regurgitation International DAtabase (MIDA) is a multicentre registry of MR due to flail leaflets including 862 patients (65 ± 12 years) diagnosed by echocardiography. The 498 older patients (≥65 years at diagnosis) were compared with the 364 younger (<65) with regard...

CONTEXT Mortality among human immunodeficiency virus (HIV)-infected individuals has decreased dramatically in countries with good access to treatment and may now be close to mortality in the general uninfected population. OBJECTIVE To evaluate changes in the mortality gap between HIV-infected individuals and the general uninfected population. DESIGN, SETTING, AND POPULATION Mortality follow...

Seasonal fluctuations in mortality are associated with age, outdoor temperature, and influenza. The relative excess winter mortality is approximately twice as high in the UK compared with the Scandinavian countries. Using data from Norway and England plus Wales, this study compares the effect of age, temperature and influenza on winter excess mortality in the two countries. Bivariate analyses s...

OBJECTIVES The purpose of this study was to assess the effects of recent influenza epidemics on mortality in Japan. METHODS We applied a new definition of excess mortality associated with influenza epidemics and a new estimation method (new method) proposed in our previous paper to the national vital statistics for 1975-1999 (ICD8-ICD10 had been adopted) in Japan. This new method has the adva...

BACKGROUND Climate change is anticipated to influence heat-related mortality in the future. However, estimates of excess mortality attributable to future heat waves are subject to large uncertainties and have not been projected under the latest greenhouse gas emission scenarios. OBJECTIVES We estimated future heat wave mortality in the eastern United States (approximately 1,700 counties) unde...

BACKGROUND The Downtown Eastside is a robust and densely populated neighbourhood in Vancouver, Canada, that is characterized by low-income housing and drug use and a high prevalence of HIV infection. We evaluated mortality and excess mortality among the broader community of individuals living in this neighbourhood. METHODS The Community Health and Safety Evaluation is a community-based study ...

BACKGROUND While prior studies have quantified the mortality burden of the 1957 H2N2 influenza pandemic at broad geographic regions in the United States, little is known about the pandemic impact at a local level. Here we focus on analyzing the transmissibility and mortality burden of this pandemic in Arizona, a setting where the dry climate was promoted as reducing respiratory illness transmis...

BACKGROUND Heatwaves could cause the population excess death numbers to be ranged from tens to thousands within a couple of weeks in a local area. An excess mortality due to a special event (e.g., a heatwave or an epidemic outbreak) is estimated by subtracting the mortality figure under 'normal' conditions from the historical daily mortality records. The calculation of the excess mortality is a...

We discovered an emerging non-metropolitan mortality penalty by contrasting 37 years of age-adjusted mortality rates for metropolitan versus nonmetropolitan US counties. During the 1980s, annual metropolitan-nonmetropolitan differences averaged 6.2 excess deaths per 100,000 nonmetropolitan population, or approximately 3600 excess deaths; however, by 2000 to 2004, the difference had increased mo...