Abstract Inducers play an important role in fungus cellulase production. In this study, a combination of Avicel and laver powder, which contains cellulose, hemicellulose, other polysaccharides, crude lipid, was used to induce lignocellulolytic enzyme production Penicillium piceum H16. When supplemented with various amounts activities or extracellular protein yields increased by 11.4%–102.5%, re...

Macrophages, which secrete proteolytic enzymes capable of hydrolyzing elastin, collagen, and glycoproteins, may play a prominent role in the turnover of connective tissue macromolecules at inflammatory sites. Their degradative capacity has been demonstrated on purified connective tissue substrates (1-6) and on complex extracellular matrices produced by cultured smooth muscle cells (SMC), x fibr...

An extracellular lipase from Amycolatopsis mediteranei (AML) with potential applications in process biotechnology was recently cloned and examined this laboratory. In the present study, 3D structure of AML elucidated by comparative modelling. lacked 'lid' observed most true lipases shared similarities plastic degrading enzymes. Modelling substrate specificity studies showed that a cutinase rela...

Macrophages, which secrete proteolytic enzymes capable of hydrolyzing elastin, collagen, and glycoproteins, may play a prominent role in the turnover of connective tissue macromolecules at inflammatory sites. Their degradative capacity has been demonstrated on purified connective tissue substrates (1-6) and on complex extracellular matrices produced by cultured smooth muscle cells (SMC), x fibr...

The gram-positive spore-forming bacteria, Bacillus thuringiensis (Bt) strains produced novel cellulases which could liberate glucose from soluble cellulose, carboxymethyl cellulose (CMC), and insoluble crystalline cellulose. The maximal cellulase activities were obtained after 60 hrs incubation at 28oC in a LB broth medium with 1% CMC. Maximum CMCase activities were got at 40oC and pH 4.0, resp...

Microbial xylanase and pectinase are two extremely valuable enzymes, which have captivated much attention. This can be seen from the increased demand for these enzymes by many industrial sectors. This study investigates the isolation and screening of extracellular xylanopectinolytic enzymes-producing bacteria in a submerged fermentation (SmF). Samples are collected from the compost of empty fru...

The chemical structure of organic matter has been shown to be only marginally important for its decomposability by microorganisms. The question of why organic matter does accumulate in the face of powerful microbial degraders is thus key for understanding terrestrial carbon and nitrogen cycling. Here we demonstrate, based on an individual-based microbial community model, that social dynamics am...

Halobacterium strains produce a truly extracellular proteinase which degrades gelatine and casein. It has a pH optimum of about 8 and depends upon divalent cations and a high concentration of NaCl or KC1 for activity and stability. Proteolytic enzymes were also found in cell homogenates obtained by ultra sonic treatment. A caseinolytic enzyme, probably different from the extracellular one, is a...

Fibrosis, or excessive scarring, is characterized by the emergence of alpha-smooth muscle actin (αSMA)-expressing myofibroblasts and accumulation fibrotic extracellular matrix (ECM). Currently, there a lack effective treatment options for fibrosis, highlighting an unmet need to identify new therapeutic targets. The acquisition phenotype associated with changes in chromatin structure, key determ...