PURPOSE To define MR characteristics of primary extramedullary plasmacytoma in the head and neck using a variety of plain and contrast-enhanced MR protocols. METHODS Six patients with primary extramedullary plasmacytoma in the head and neck were examined clinically and with MR imaging at 1.5 T. The morphologic appearance and signal intensities of the lesions were analyzed and the results of t...

Extramedullary plasmacytomas are rare tumors. In majority of cases tumors arise in the head and neck region and endobronchial localization is extremely rare. The treatment is usually resection alone or combination of surgery with radiotherapy. Herein we present a case of solitary endobronchial plasmacytoma which was resected with bronchoscopic electrocautery, because of extremely rare occurrenc...

Plasma cell neoplasms of the head and neck region can be extramedullary plasmacytoma of the bone, solitary plasmacytoma of the bone, and local manifestations of multiple myeloma. A 70-year-old male patient was admitted to our hospital with diplopia of four-day history. Magnetic resonance imaging showed soft tissue in the sphenoid sinus. Endoscopic biopsy was taken from the sphenoid sinus, which...

Laryngeal plasmacytoma is rare in Japan; to the best of our knowledge, only 8 other cases have been previously reported. We report a new case of extramedullary plasmacytoma of the larynx in a 76-year-old Japanese woman. Immunohistochemical investigation revealed that her disease had not progressed to multiple myeloma. The patient declined radiotherapy, and her condition remained stable at the 6...

Plasmacytoma is a plasma cell neoplasm that locally infiltrates a bone or spreads to extramedullary areas. A new World Health Organization criterion defines solitary plasmacytoma of bone as a localized bone tumor consisting of plasma cells identical to those seen in plasma cell myeloma, which is manifested as a solitary osteolytic lesion in a radiological evaluation. Primary tumors of the stern...

A 29-year-old woman with a history of a maxillary plasmacytoma treated with radiation therapy presented with painless jaundice. A computed tomography (CT) scan revealed biliary dilatation and diffuse pancreatic enlargement suggestive of pancreatitis. Percutaneous transhepatic cholangiography demonstrated encasement of the distal common bile duct by an extrinsic mass. At exploratory laparotomy, ...

Primary plasmacytoma of the bladder is extremely rare, with only 10 cases reported in the literature. We report on a patient who was treated unsuccessfully with radiation and subsequently underwent anterior exenteration with ileo-conduit construction.

BACKGROUND Extraosseous plasmacytoma, so called extramedullary plasmacytoma (EMP) is relatively rare in China. The aim was investigate the clinicopathologic features of EMP and the role of Immunophenotype and genotype detection in diagnosis of EMP. METHODS Thirty-two cases of EMP were investigated retrospectively by histopathology, immunophenotype, genotype and survival analysis. RESULTS Cl...

Plasma cell neoplasms include various conditions ranging from indolent such as monoclonal gammopathy of undetermined significance (MGUS) to more aggressive forms multiple myeloma (MM). The World Health Organization classifies plasmacytomas into two types: solitary osseous plasmacytoma (SOP) and extramedullary (EMP). Most primary EMPs occur in the upper gastrointestinal tract, head neck, respira...

Extramedullary plasmacytomas are plasma cell neoplasms in organs other than the bone marrow. Most are found in the upper respiratory tract. Involvement of the pancreas is rare. We report a case of pancreatic plasmacytoma in association with advanced multiple myeloma.