The control of tissue growth, which is a key to maintain the protective barrier function of the epithelium, depends on the balance between cell division and cell extrusion rates [1, 2]. Cells within confluent epithelial layers undergo cell extrusion, which relies on cell-cell interactions [3] and actomyosin contractility [4, 5]. Although it has been reported that cell extrusion is also dependen...

The objective of this paper is to investigate the viscous shear heating effect on the formation of minimum film thickness in inlet zone of the hydrostatic extrusion process as function of various operating parameters. Minimum film thicknesses in the inlet zone has been evaluated at various extrusion speeds, material parameters, extrusion pressures, and die semiangle for extrusion of low strengt...

This paper presents a new interpretation of the binary blending operator of implicit modeling. Instead of considering the operator as a composition of potential functions, we propose to consider it as an implicit curve extruded in an implicit extrusion field. An implicit extrusion field is a 2D space for which each coordinate is a potential field. The study of general concepts around implicit e...

Abstract Epithelial monolayers play an important role in a broad range of physiological and pathological processes, such as embryonic development wound healing. become crowded during cell proliferation growth, however, their mechanical properties entities remain obscure. This paper presents novel efficient method utilizing the structural stiffness matrix-based computational (SMM) to investigate...

In the present study the effect of phase volume fraction on the reinforcement of microstructure and tensile properties of composite extrusion process Al6061/SiC has been studied. For this purpose, the base alloy Al6061 using pure aluminum ingots, silicon, of Al-50% Mg, Al-10% Cr and a thin copper rod was prepared. Next, the composite Al6061/5% SiC, Al6061/10% SiC, Al6061/15% SiC and Al6061/20% ...

Low-temperature incipient melting and high deformation resistance of aluminium alloy AA7075 place extraordinary demands on extrusion die design and process optimization, especially when the shape of the extrudate is complex. The present case study was aimed at combining the considerations on die design and process optimization for the alloy to manufacture a complex solid profile with large diff...