This paper reflects results of research into the use of factorial experimental design for rational constructing sensitivity and functionally oriented models for system optimization and control. The questions of overcoming difficulties of statistical evaluating the results of experiments with models of systems, but not real systems are discussed. The results of the paper are of a universal chara...

We give a combinatorial interpretation for the super Catalan number S(m,m + s) for s ≤ 3 using lattice paths and make an attempt at a combinatorial interpretation for s = 4. We also examine the integrality of some factorial ratios.

In this work, the production of fungal laccase was optimized from local isolate of Pleurotus ostreatus using solid state fermentation. Factorial design was used to study the effect of several nutrients on enzyme production. Purification and characterization of the enzyme and the effect of temperature, pH and gamma radiation on fungal growth and enzyme production was investigated. Optimization o...

Liposomal carriers, eminent for their potential in topical drug delivery have been chosen to help embedding of nystatin molecules in the skin layers. The objective of present study was to develop and carry out rheological investigations of nystatin liposomal gel by using optimization technology in terms of 2 factorial design. In this study attempts have been made to formulate liposomal dispersi...

The effect of the Transcendental Meditation (TM) technique on working memory and field independence was investigated in a twelve-week longitudinal time-series study in which the uMatch Me" computerized memory game and the Rod and Frame Test were administered daily to a matched pair of 11-year-old boys and a matched pair of 14-year-old girls. One of the boys and one of the girls began the TM tec...

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the objective of this work was to develop bioadhesive topical gel of aceclofenac with the help of response-surface approach. experiments were performed according to a 3-level factorial design to evaluate the effects of two independent variables [amount of poloxamer 407 (pl-407 = x1) and hydroxypropylmethyl cellulose k100 m (hpmc = x2)] on the bioadhesive character of gel, rheological property o...

A diallel cross is a set of all possible matings between several genotypes, which may be individuals, clones, homozygous lines, etc. Such crosses are used to estimate general and specific combining abilities of lines and crosses respectively. For ‘n’ inbreed lines, the possible F1’s are n(n–1)/2, which are to be tested in a suitably replicated randomized design. With facilities available for te...

We present a design of experiments (DOE) technique for microwave/millimeter wave flip chip characterization and optimization. Two optimization approaches, signal bump misalignment and transmission line compensation, are combined together for optimal performance for high frequency operation. First, the design of experiments method is presented and its advantages are emphasized. Then, the two tec...

BACKGROUND The 2 × 2 factorial design is widely used for assessing the existence of interaction and the extent of generalizability of two factors where each factor had only two levels. Accordingly, research problems associated with the main effects and interaction effects can be analyzed with the selected linear contrasts. METHODS To correct for the potential heterogeneity of variance structu...