background: in oil refinery plants, shift working is inevitable . shift work is associated with depression; therefore this prospective study was carried out in tehran shahid tondguyan oil refinery in order to determine the prevalence of depression in shift workers and to assess the effects of associated factors with depression among shift workers. in the present study, the shifting work system ...

Next generation sequencing technologies enable rapid, large-scale production of sequence data sets. Unfortunately these technologies also have a non-neglible sequencing error rate, which biases their outputs by introducing false reads and reducing the quantity of the real reads. Although methods developed for SAGE data can reduce these false counts to a considerable degree, until now they have ...

The ability to sequence mitochondrial genomes quickly and cheaply has led to an explosion in available mtDNA data. As a result, an expanding literature is exploring links between mtDNA features and susceptibility to, or prevalence of, a range of diseases. Unfortunately, this great technological power has not always been accompanied by great statistical responsibility. I will focus on one aspect...

In vitro experiments were conducted to determine whether the direct thrombin inhibitors argatroban and lepirudin can interfere with the results of lupus anticoagulant (LA) testing. Concentration-response curves were generated to calculate the concentration of anticoagulant that prolongs the activated partial thromboplastin time (aPTT) to 75 seconds (2.5 times the baseline average). Correspondin...

Coordinate based meta-analysis (CBMA) is used to find regions of consistent activation across fMRI and PET studies selected for their functional relevance to a hypothesis. Results are clusters of foci where multiple studies report in the same spatial region, indicating functional relevance. Contrast meta-analysis finds regions where there are consistent differences in activation pattern between...

Most widely used geometric correction methods rely on ground control points to empirically determine a mathematical coordinate transformation to project the distorted image into the reference image. However, conventional methods usually employed the same correction formula in the whole image which few considered the seriously geometric distortion problem causing by imaging with a large view ang...