To develop a method for the early diagnosis of health damage due to arc welding, we measured serum ferritin in 96 general employees and 320 arc welders in Company A. A positive correlation was observed between age and the serum ferritin level in the young group (age, 20 44 years) among the general employees. The mean serum ferritin level in the general employees was 119 ± 56 ng/ml. When the mea...

Ferritin is a positive acute phase reactant, exhibiting increased levels in blood during the acute phase response. Nevertheless, the precise role of ferritin as an acute phase reactant remains to be clarified. As for other acute phase proteins, ferritin is produced and secreted by hepatocytes. However, ferritin is also produced and secreted by other cell types, including macrophages and cancer ...

Recent reports have described families in whom a combination of elevated serum ferritin not related to iron overload and congenital nuclear cataract is transmitted as an autosomal dominant trait. We have studied the molecular pathogenesis of hyperferritinemia in two families showing different phenotypic expression of this new genetic disorder. Serum ferritin levels ranged from 950 to 1,890 micr...

BACKGROUND Ferritin constitutes a sensitive iron-storage index and multi-functional protein. Evidence on its association with mortality in general population is scarce and conflicting. We investigated the sex-specific associations of ferritin levels with all-cause and cardiovascular mortality in a population-based cohort. METHODS Data came from the English Longitudinal Study of Ageing and the...

The possibility that serum ferritin is a secreted protein and an acute phase reactant regulated by inflammatory hormones and iron was examined in a hepatic cell line that secretes plasma proteins. Differentiated rat hepatoma cells released albumin and ferritin into the medium, as determined by rocket immunoelectrophoresis and isolation of ferritin by standard procedures plus immunoaffinity chro...

The interactions of horse spleen ferritin and its derivative apoferritin with H+ ions were studied by potentiometric and spectrophotometric titration; to aid in data analysis, heats of ionization over a limited pH range and amide content were also determined. Per apoferritin subunit, all tyrosine and cysteine side chains, two of the nine lysine side chains and at least three of the six histidin...

BACKGROUND Ferritin is a high molecular weight protein which reflects body iron stores, but may also rise in the case of an acute phase response. Recently, ferritin has been identified as a predictive factor in the development and progression of atherosclerosis. This is the first report on serum ferritin levels in patients with proteinuria. METHODS We have analysed the data of 142 male patien...

AIMS To determine a concentration of ferritin below which the possibility of iron deficiency should be considered in elderly patients. METHODS Consecutive new referrals to a geriatric unit (n = 472) were studied prospectively. Full blood count, ferritin, serum vitamin B12 and red cell folate were measured for all patients. A blood film was assessed independently by three haematologists for fe...

some recent studies have revealed the relationship among excess ferritin, coronary heart disease, and insulin resistance. to assess the association between serum ferritin concentration and impaired fasting glucose, this study was designed. a total of 187 people including 91 impaired fasting glucose (ifg) subjects and 96 normal glucose subjects who had been recognized in a large epidemiological ...

background iron-loaded cardiac complication is the essential cause of mortality in patients with thalassemia. early detection and treatment of cardiac over-load can reduce mortality. objectives the current study aimed to evaluate the relationship between serum ferritin levels and t2* magnetic resonance imaging (mri) of heart and liver and liver iron concentration (lic) to diagnose iron over loa...