Although several inherited melanoma predisposition syndromes have been identified, a subset of families lack pathogenic variants in known highly penetrant genes, including CDKN2A, CDK4, and BAP1. We describe patient with multiple melanomas other primary tumors germline variant BUB1B. A 76-year-old woman presented history multiple, distinct tumors, childhood thymoma, thyroid cancer, two melanoma...

Several studies have shown that decidual tissue produces soluble factors which can mediate a variety of immunosuppressive activities. In order to assess whether prostaglandin E2 (PGE2) was present in supernatants produced by explant culture of 10 human specimens of first trimester decidua. The effect of the supernatants from the two different series (with and without indomethacin treatment) ...

Background: High maternal hemoglobin (Hb) concentration was considered a risk factor for the developing of pregnancy hypertension. The purpose of this study was to determine whether high maternal Hb concentration in first trimesters associated with pregnancy induced hypertension in Iranian nulliparous women. Methods: This study was carried out in teaching hospital in Sari, Iran. Samples were ob...

Abstract Polycystic ovarian syndrome (PCOS) is a common cause of subfertility particularly when anovulation present. In this circumstance efforts are made to induce ovulation through lifestyle modification, medication, or combination both. Other patients with PCOS may be ovulatory but require IVF/ICSI for other causes, including male factor tubal infertility. all cases, attention needs placed o...

We calculate the electromagnetic form factor of the pion in quenched lattice QCD. The non-perturbatively improved Sheikoleslami-Wohlert lattice action is used together with the O(a) improved current. We calculate form factor for pion masses down to mπ = 360 MeV . We compare the mean square radius for the pion extracted from our form factors to the value obtained from the ’Bethe Salpeter amplitu...