Analytical techniques employed in modern methods of substance analysis are essentially derived from the foundation science of atomic and molecular absorption spectroscopy which deals with the theory and interpretation of optical spectra (a.k.a. the quantitative and qualitative study of elements and compounds). Some of the familiar technologies which are based in spectroscopy are: Clinical Chemi...

A simple format for microscale chemical assays is proposed. It does not require the use of test tubes, microchips or microtiter plates. Microlitre-range (ca. 0.7-5.0 μL) aqueous droplets are generated by a commercial micropipette in a non-polar matrix inside a Petri dish. When two droplets are pipetted nearby, they spontaneously coalesce within seconds, priming a chemical reaction. Detection of...

BACKGROUND Hydrophobic interaction chromatography (HIC) most commonly requires experimental determination (i.e., scouting) in order to select an optimal chromatographic medium for purifying a given target protein. Neither a two-step purification of untagged green fluorescent protein (GFP) from crude bacterial lysate using sequential HIC and size exclusion chromatography (SEC), nor HIC column sc...

An illuminated Book of Hours (in use in Chalon-sur-Saône) currently owned by the Museo Civico di Arte Antica and displayed prestigious Palazzo Madama Torino (Italy) was investigated means optical microscopy, fibre optic reflectance spectroscopy, molecular fluorimetry, X-ray fluorescence spectrometry Raman spectroscopy. The aim scientific survey to expand knowledge manuscript itself on materials...

Abstract Mixed micellar systems have been tried with the aim of achieving higher solubility drugs compared to single systems. Hydrophobic-hydrophilic mixed used for above purpose drug ciprofloxacin in past. In present study, a hydrophilic-hydrophilic binary system comprising pluronic copolymers F127 and L64 has studied its effect on solubilization Ciprofloxacin. The solutions two individual the...

Glioblastoma is the most frequent and aggressive primary brain tumor. Its diagnosis based on resection or biopsy that could be especially difficult dangerous in case of deep location patient comorbidities. Monitoring disease evolution progression also requires repeated biopsies are often not feasible. Therefore, there an urgent need to develop biomarkers diagnose follow glioblastoma a minimally...