Treatment of tuberculosis (TB) and the discovery of effective new anti tubercular drugs is one of the most urgent priorities in health organizations all around the world. In the present study, fluorinated analogs of some of the most important anti-TB agents such as p-aminosalicylic acid (PAS), thiacetazone and pyrazinamide were synthesized and tested against TB. The fluorinated analog of thiace...

Treatment of tuberculosis (TB) and the discovery of effective new anti tubercular drugs is one of the most urgent priorities in health organizations all around the world. In the present study, fluorinated analogs of some of the most important anti-TB agents such as p-aminosalicylic acid (PAS), thiacetazone and pyrazinamide were synthesized and tested against TB. The fluorinated analog of thiace...

We present refined coordinates and proper-motion data for the high proper-motion (HPM) stars in the Luyten Half-Second (LHS) catalog. The positional uncertainty in the original Luyten catalog is typically greater than 1000 and is often greater than 3000. We have used the digital scans of the POSS I and POSS II plates to derive more accurate positions and proper motions of the objects. Out of th...

An unmet need exists for the development of next-generation multifunctional nanocomposite materials for biomedical applications, particularly in the field of cardiovascular regenerative biology. Herein, we describe the preparation and characterization of a novel polyhedral oligomeric silsesquioxane poly(carbonate-urea) urethane (POSS-PCU) nanocomposite polymer with covalently attached anti-CD34...

A new approach is presented for detecting whether a particular computation of an asynchronous distributed system satis es Poss (read \possibly "), meaning the system could have passed through a global state satisfying predicate , or Def (read \de nitely "), meaning the system de nitely passed through a global state satisfying . Detection can be done easily by straightforward state-space search;...

Polyamide 6 (PA6) and short glass fiber (SGF) reinforced PA6 composites toughened with glycidylisobutyl oligomeric silsesquioxane (G-POSS) and 1.10-carbonyl-bis-caprolactam (CBC) were prepared by meltextrusion compounding process and then compounds were formed to 2 mm thick double edge notched tension samples (DENT) by injection moulding process. Fracture properties of composites were analyzed ...

Herein, we applied the Illumina MiSeq pyrosequencing platform to amplify V3–V4 hypervariable regions of 16 S rRNA gene gut microbiota (GM) and a gas chromatograph–mass spectrometer detect metabolites after supplementation with pumpkin oligosaccharides (POSs) determine metabolic markers mechanisms in rats type 2 diabetes (T2D). The POSs alleviated glucolipid metabolism by decreasing serum low-de...

A new hybrid thermoplastic polyurethane (TPU) system that incorporates an organic, biodegradable poly(D, L-lactide) soft block with a hard block bearing the inorganic polyhedral oligosilsesquioxane (POSS) moiety is introduced and studied. Changes in the polyol composition made through variation of the hydrophilic initiator molecular weight show direct control of the final transition temperature...

The process of insertion of molecular oxygen and nitrogen into polyhedral oligomeric silsesquioxanes (POSS) has been investigated theoretically. Using ab initio methods, the N2interaction with the POSS has been described with restricted Hartree−Fock (RHF) with a triple-ζ basis set, while systems involving O2 require restricted open shell (ROHF) wave functions, to account for their open-shell gr...