The flux distribution in a detailed metabolic network of CHO-320 cells is evaluated using Metabolic Flux Analysis. As in many practical situations, the available information is not sufficient to completely define the metabolic fluxes, and so, the mass balance system of equations is underdetermined. However, the measurements of the time evolution of a number of extracellular components can provi...

We better determine the spectral flux distribution of the supernova candidate associated with GRB 970228 by modeling the spectral flux distribution of the host galaxy of this burst, fitting this model to measurements of the host galaxy, and using the fitted model to better subtract out the contribution of the host galaxy to measurements of the afterglow of this burst.

Interactions between the structure of a metabolic network and its functional properties underlie its evolutionary diversification, but the mechanism by which such interactions arise remains elusive. Particularly unclear is whether metabolic fluxes that determine the concentrations of compounds produced by a metabolic network, are causally linked to a network's structure or emerge independently ...