نتایج جستجو برای: forced swimming model
تعداد نتایج: 2156929 فیلتر نتایج به سال:
Introduction: Rosa Damasca essential oil is currently used as anti-depressant in animal models and human. Considering the similarities between Rosa Canina and Rosa Damasca, the effects of water and alcoholic extracts of R. Canina on depression induced by forced swimming test (FST) in mice were investigated. Methods: Male NMRI mice (25-30 g) were used (n=6/group). Intraperitoneal injections o...
Introduction: Studies show that chronic stress can lead to anxiety and depression. Basil (Ocimum basilicum L.) has antioxidant, anti-inflammatory, anti-apoptotic, anti-diabetic and anti-nociceptive properties. The aim of this study was to investigate the effect of basil hydro-alcoholic extract on chronic restraint stress-induced anxiety and depression in male Wistar rats. Methods: In this...
Perillae Herba (a leaf of Perilla frutescens) has been prescribed as one of the component herbs in certain Kampo (Japanese herbal) medicines that are used clinically for the improvement of depressive mood. l-Perillaldehyde (PAH) is a major component in the essential oil containing in Perillae Herba, but its antidepressant-like effect has not been reported. To clarify the antidepressant-like eff...
In the present study, we have investigated the effects of silymarine on depression and the possible role of serotonergic system in these effects. The rats were anesthetized intraperitoneally with ketamine hydrochloride and placed in a Stoelting stereotaxic instrument. A stainless steel guide cannula (22-gauge) was implanted in the third ventricular region. The third ventricular region was infus...
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