نتایج جستجو برای: franz cell diffusion

تعداد نتایج: 1833469  

Journal: :Pharmaceutics 2023

In this study, we examined and compared two different lipid-based nanosystems (LBNs), namely Transferosomes (TFs) Monoolein Aqueous Dispersions (MADs), as delivery systems for the topical application of Ferulic Acid (FA), an antioxidant molecule derived from natural sources. Our results, demonstrated through Franz-cell experiments, indicate that LBNs produced with poloxamer 188 in their composi...

2011
N Akhtar MU Rehman HMS Khan

Purpose: To investigate the penetration enhancing effect of two polysorbates polyoxyethylene 20 (POE-20) and polyoxyethylene 80 (POE-80) on the in vitro percutaneous absorption of ascorbic acid (AA). Methods: For the permeation experiments, Franz diffusion cell covered with aluminum foil providing an effective diffusion area of 1.76 cm 2 and hairless rabbit skin were used. A range of concentrat...

Journal: :Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2010
Bram Baert Jente Boonen Christian Burvenich Nathalie Roche Filip Stillaert Phillip Blondeel Jan Van Boxclaer Bart De Spiegeleer

PURPOSE In vitro skin/membrane permeation profiling of topical pharmaceuticals is an important overall quality attribute in the evaluation of product consistency and it is also used for IVIVR (in vitro - in vivo relationship) purposes in product development and change control. Franz diffusion cell (FDC) experiments are emerging as a generally accepted methodology in this field, where the choice...

Journal: :Journal of Approximation Theory 2011
András Kroó Paul Nevai Vilmos Totik

Franz Peherstorfer was born in Zwettl an der Rodl, a village near Linz, the provincial capital of Upper Austria. After attending elementary and secondary schools in and around Linz, he matriculated in the newly founded Johannes Kepler Universität Linz1 in 1970 where he obtained his university degrees, Masters (1975) and Ph.D.2 (1977), both with summa cum laude. He was appointed as Assistent the...

2015
J. Chifamba A. Dube C. C. Maponga

The skin penetration and safety of nanometric zinc oxide and titanium dioxide incorporated in a cosmeceutical cream, specifically designed to retard skin actinic damage in tropical Oculocutaneous albinism was investigated ex-vivo through simulated actinically damaged porcine skin. Franz diffusion cells were used in an experiment modeled in line with related work done by Diembeck et al (1999); t...

2017
Ching-Yun Hsu Shih-Chun Yang Calvin T Sung Yi-Han Weng Jia-You Fang

Pathogens usually invade hair follicles when skin infection occurs. The accumulated bacteria in follicles are difficult to eradicate. The present study aimed to assess the cutaneous and follicular delivery of chloramphenicol (Cm)-loaded liposomes and the antibacterial activity of these liposomes against methicillin-resistant Staphylococcus aureus (MRSA). Skin permeation was conducted by in vitr...

Journal: :Acta poloniae pharmaceutica 2014
Dorota Szura Łukasz Ozimek Magdalena Przybyło Katarzyna Karłowicz-Bodalska Ewa Jaźwińska-Tarnawska Anna Wiela-Hojeńska Stanisław Han

The possibility of applying liposomes as a topical drug delivery system is still a matter of intensive research. The purpose of this study was to determine the suitability of liposomes as carriers of naproxen and to prove their impact on the effectiveness of transdermal permeation of an active substance. The study was conducted with the use of Franz Diffusion Cell System by comparing the effica...

2006
ALKA AHUJA R. K. KHAR

In the present study, an attempt was made to develop a low-dose controlled-release delivery system for the treatment of periodontal infections. Nylon fibres were taken as core material. The coating solution contained polyvinyl acetate and amoxycillin trihydrate. The fibres were coated five times to maximize drug loading. The coating composition was optimized and fibres were subjected to in vitr...

Journal: :Investigative ophthalmology & visual science 2017
Rosemary S Cuming Eva M Abarca Sue Duran Anne A Wooldridge Allison J Stewart William Ravis R Jayachandra Babu Yuh-Jing Lin Terri Hathcock

Purpose To determine in vitro release profiles, transcorneal permeation, and ocular injection characteristics of a voriconazole-containing thermogel suitable for injection into the subconjunctival space (SCS). Methods In vitro release rate of voriconazole (0.3% and 1.5%) from poly (DL-lactide-co-glycolide-b-ethylene glycol-b-DL-lactide-co-glycolide) (PLGA-PEG-PLGA) thermogel was determined fo...

2015
Vajihe Akbari Daryoush Abedi Abbas Pardakhty Hojjat Sadeghi-Aliabadi

BACKGROUND Development of new drug carriers would be an interesting approach if it allowed increased efficacy of antibiotics and a reduction in doses, thus reducing the risk of developing resistance. As with most drug carriers, niosomes have been used to improve the selective delivery and the therapeutic index of antimicrobial agents. METHODS In this study, different formulation of niosomes c...

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