In this study, two different dust collectors, one based on an inertial separator and the other electrostatic precipitator (ESP), were developed in order to reduce brake wear particulate matter (PM) emissions. Additionally, collection efficiencies for particles (BWPs) of ESP evaluated according pad type. case separator, BWP low-metallic (LM) non-asbestos organic (NAO) pads similar, cut-off size ...

In the braking system, heat dissipation generated by friction between disc and pad should be evacuated as quickly possible. this work, five common different automotive brakes were studied through mathematical theories of transfer numerical methods using ANSYS software. addition, a direct comparison experimental, theoretical, simulation values found in open literature was performed to propose br...

Exhaust regulations and improved exhaust gas treatment systems have already initiated the trend that brings emissions from brakes tires to forefront of traffic-induced particulate matter. The health environmental relevance matter has resulted in regulators, industry, research institutions prioritising mitigation non-exhaust particle emissions. To this end, under umbrella United Nations Economic...

Glaucoma is a progressive neuropathy characterized by loss of vision as a result of retinal ganglion cell (RGC) death. There are no effective neuroprotectants to treat this disorder. Brain-derived neurotrophic factor (BDNF) is well known to transiently delay RGC death in ocular hypertensive eyes. The CNS-specific leucine-rich repeat protein LINGO-1 contributes to the negative regulation to some...

More than 50% of multiple sclerosis patients develop cognitive impairment. However, the underlying mechanisms are still unclear, and there is no effective treatment. LINGO-1 (LRR and Ig domain containing NOGO receptor interacting protein 1) has been identified as an inhibitor of oligodendrocyte differentiation and myelination. Using the experimental autoimmune encephalomyelitis (EAE) mouse mode...

The ever growing size of chemical databases calls for the development of novel methods for representing and comparing molecules. One such method called LINGO is based on fragmenting the SMILES string representation of molecules. Comparison of molecules can then be performed by calculating the Tanimoto coefficient, which is called LINGOsim when used on LINGO multisets. This paper introduces a ve...

Multiple sclerosis (MS) is an autoimmune-inflammatory disease of the central nervous system (CNS) with prominent demyelination and axonal injury. While most MS therapies target the immunologic response, there is a large unmet need for treatments that can promote CNS repair. LINGO-1 (leucine-rich repeat and Ig-containing Nogo receptor interacting protein-1) is a membrane protein selectively expr...