BACKGROUND Several studies have demonstrated a short-term antiproteinuric effect of mineralocorticoid receptor blockers (MRB) on proteinuric kidney diseases, but no information is available about the long-term persistence (>1 year) of such reduction in proteinuria and the long-term effects of MRB on renal function. METHODS We prospectively studied the effects of adding spironolactone (25 mg/d...

Dilution as a model of forgetting 2 Abstract We develop a model of long term forgetting based upon three ideas: i) Memory for a stimulus can be described by a population of accessible traces; ii) The probability of retrieval after a delay is predicted by the proportion of traces in this population that will be defined as correct if sampled; and iii) This population is diluted over time by null ...

Researchers use spatiotemporal measurements of brain activity obtained from methods such as functional magnetic resonance imaging (MRI), positron emission tomography (PET), and electroencepholagraphy (EEG) in neuroscience to aid in understanding how different regions of the brain respond to stimuli. In a typical experiment, a subject receives some stimulus, such as a visual or auditory cue, and...

These lectures will cover methods for studying the evolution of galaxies since their formation. Because the properties of a galaxy depend on its history, an understanding of galaxy evolution requires that we understand the dynamical interplay between all components over 10 gigayears. For example, lopsided (m = 1) asymmetries are transient with gigayear time scales, bars may grow slowly or sudde...

A new mechanism for the pp → ppπ reaction close to threshold is suggested coming from the isoscalar excitation of the Roper and its decay into N(ππ)s−wave, with one of the π 0 emitted and the other one reabsorbed on the second nucleon. The mechanism can lead to important interference with other mechanisms and, together with experiment, serves to exclude large ranges of the 2π N decay parameters...

This paper reconsiders the uniform sublevel set estimates of Carbery, Christ, and Wright [5] and Phong, Stein, and Sturm [17] from a geometric perspective. This perspective leads one to consider a natural collection of homogeneous, nonlinear differential operators which generalize mixed derivatives in R. As a consequence, it is shown that, in the case of both of these previous works, improved u...

Supersymmetric models are typically taken to have p parameter and all soft supersymmetry breaking parameters at or near the weak scale. We point out that a small window of allowed values exists in which ~1 and the electroweak gaugino masses are in the few GeV range. Such models naturally solve the supersymmetry CP problem, can reduce the discrepancy in &,, and suppress proton decay. In this win...

We study the asymptotic behaviour of solutions to the porous media equation in an exterior domain, Ω, which excludes one or several holes, with zero Dirichlet data on ∂Ω. We prove that, when the space dimension is three or more, this behaviour is given by a Barenblatt function away from the fixed boundary ∂Ω and near the free-boundary. On the other hand, if we scale the solution according to it...

background: prevalence of fall-related mortality is rising in the elderly population. falling is one of the causes of the murderous and non-murderous injuries in the elderly population which can lead to disability, dependence and decline of quality of life. fractures constitute a major part of the fall-related injuries. the present study is designed to investigate the prevalence of fall-related...