Functional gastrointestinal disorders (FGIDs) are characterised by visceral pain or discomfort with an unknown cause. There is increasing evidence for abnormal processing of sensory input in FGIDs. Modulation of sensory input occurs at all levels of the nervous system, with a dynamic balance between facilitation and inhibition and close integration with the body's wider homoeostatic control. Co...

background : psychological factors have important role in vulnerability and maintenance of functional gastrointestinal disorders (fgid). the aims of present study was the comparison of early maladaptive schemas and cognitive emotion regulation styles in fgid patients and normal group. materials and method : for this purpose from functional gastrointestinal disorders population that referred to ...

aim and background: it has since long been known that there is strong relation between   psychological status and functional gastrointestinal disorders (fgid). however, until recently, the nature of this putative relationship was unclear due to a lack of non-invasive methods to investigate the neurobiological mechanisms underlying this relationship.  functional brain imaging has provided a meth...

AIM To investigate the intestinal luminal microbiota (LM) and mucosa-associated microbiota (MAM) in Chinese patients with functional gastrointestinal disorders (FGIDs) and examine the association between these communities and the expression of toll-like receptor (TLR) 2 and TLR4. METHODS Thirty-two Chinese subjects who suffered from symptoms of FGIDs, as confirmed by gastroenterologists, were...

| LEADING ARTICLE | PAIN MANAGEMENT IN IBD 1 Address for correspondence: Address for correspondence: Douglas A Drossman, MD, Professor of Medicine and Psychiatry, Co-Director UNC Center for Functional GI and Motility Disorders, 4150 Bioinformatics, CB#7080, University of North Carolina, Chapel Hill, NC 27599–7080, USA. Email: [email protected] Abdominal pain is a common symptom of IBD [1,2] ...

background: the unified treatment approach (up), an emotion-focused cognitive-behavioral therapy that holds emotional processes as a central target of treatment, is applicable for disorders with strong emotional components. the aim of this study was to examine the effectiveness of emotion regulation intervention derivative from the up on emotional problems and quality of life among patients wit...