The ability to post-synthetically functionalize conjugated polymers by “plugging” various structures into the polymer backbone is demonstrated in Research Article on page 2980 Alex Adronov and co-workers using inverse-electron-demand Diels–Alder (IEDDA) chemistry a poly(tetrazine) backbone. A small library of was rapidly prepared reacting series trans-cyclooctyne derivatives with poly(tetrazine).

We report a tetrazole-based, photoclick chemistry that can be employed to selectively functionalize an alkene genetically encoded in a protein inside E. coli cells. The reaction involved the treatment of E. coli cells with cell-permeable tetrazoles followed by a brief photo irradiation at 302 nm (4 min) and an overnight incubation at 4 degrees C. This in vivo alkene functionalization procedure ...

Due to the rapidity and the effectiveness of the method, the reduction of diazonium salts has been widely used to functionalize electrodes for sensor applications. However, the resulting organic film usually designed to provide complexing capabilities for the species to be determined could affect the sensor properties. The electrochemical reduction of 4methoxybenzene diazonium salt on graphite ...

We simultaneously surface-functionalize PbS nanocrystals with Cu 4,4',4'',4'''-tetraaminophthalocyanine and assemble this hybrid material into macroscopic monolayers. Electron microscopy and X-ray scattering reveal a granular mesocrystalline structure with strong coherence between the atomic lattice and the superlattice of nanocrystals within each domain. Terahertz spectroscopy and field-effect...

Protein nanoparticles are extensively investigated as versatile drug delivery systems, due to their nanoscale size, container-like shape, natural source, biocompatibility, and biodegradability. They provide three distinct interfaces: internal, external, and inter-subunit interfaces for modifications. Chemistry and genetic engineering provide powerful tools to functionalize protein nanoparticles...

Yndiamides (bis-N-substituted alkynes) are valuable precursors to azacycles. Here we report a cycloisomerization/1,2-sulfonyl migration of alkynyl-yndiamides form tetrahydropyrrolopyrroles, unprecedented heterocyclic scaffolds that relevant medicinal chemistry. This functional group tolerant transformation can be achieved using Au(I) catalysis proceeds at ambient temperature, and thermally prom...

Here we present a surfactant molecule (1) containing an ammonium headgroup, in which a bis-ureido group is incorporated in its hydrocarbon chain. Due to strong hydrogen bonding interactions, 1 forms well-defined highly ordered ribbon-like aggregates in water. Moreover, we demonstrate that these ribbons can be functionalized via a modular approach through molecular recognition of other bis-urea ...