Hydrophobins are a group of very surface-active, fungal proteins known to self-assemble on various hydrophobic/hydrophilic interfaces. The self-assembled films coat fungal structures and mediate their attachment to surfaces. Hydrophobins are also soluble in water. Here, the association of hydrophobins HFBI and HFBII from Trichoderma reesei in aqueous solution was studied using small-angle x-ray...

Background: The use of narcotics such as opium exposes addicts as susceptible targets of different diseases so that they might easily be exposed to different diseases such as fungal infections. The present study aimed to investigate the effects of addiction to opium and fungal infection on plasma levels of certain cytokines including interleukin-4 (IL-4), IL-6, IL-17, Interferon gamma (IFN-γ) a...

background and objective: otitis externa is a common condition affecting the external auditory canal. predisposing factors implicated in the pathogenesis of the condition include preexisting aural disease, genetic factors, infection, trauma, and climatic conditions. bacteria are the most common cause of infection and fungi play a smaller but significant role in the disease. otomycosis is charac...

Echinoderms are independent and quite special branch of world animals. Sea cucumbers are among the strangest members of echinoderm class regarding their structure and physiology. These fauna have been tested with regard to anti-bacterial, anti-fungal, anti-coagulants, anti-virus, cytotoxic, hemolytic and anti-HIV features. In this study, the antibacterial activity of Holothuria leucospilota...

background and objective: chronic rhinosinusitis (crs) is one of the most common chronic diseases. in the past decades, there has been an increase in fungal infections of sinuses and fungal rhinosinusitis (frs) has been diagnosed more frequently. knowing the fungal flora and its prevalence in crs patients will allow a better understanding of this disease, permitting a correct diagnosis, treatme...

beyond scholarly hair-splitting; some of the asexual Wallingford, UK: CAB International (1993). 392 pp. fungi are important causes of human disease. DNA typ-$80.00 ing recently revealed the fungal origins of Pneumocystis, an organism of great importance for AIDS patients. The Fungal Morphogenesis revolution in taxonomic knowledge raises expectations By David Moore of new strategies for disease ...

New antifungal drugs are urgently needed due to the currently limited selection, the emergence of drug resistance, and the toxicity of several commonly used drugs. To identify drug leads, we screened small molecules using a Saccharomyces cerevisiae reporter bioassay in which S. cerevisiae heterologously expresses Hik1, a group III hybrid histidine kinase (HHK) from Magnaporthe grisea. Group III...

Deep-sea hydrothermal ecosystems are considered oases of life in oceans. Since the discovery of these ecosystems in the late 1970s, many endemic species of Bacteria, Archaea, and other organisms, such as annelids and crabs, have been described. Considerable knowledge has been acquired about the diversity of (micro)organisms in these ecosystems, but the diversity of fungi has not been studied to...

Macrophomina phaseolina (Tassi) Goid is a destructive pathogen of cowpea that causes serious charcoal rot disease with significant yield losses. Antifungal activity of three indigenous Ascomycetes viz., Trichoderma harzianum, T. viride, and T. hamatum, and two Meliaceae members, i.e., Melia azedarach L. and Azadirachta indica L. were assessed against the pathogen. Laboratory screening trials wi...