Rho is a major small GTP-binding protein that is involved in the regulation of various cell functions, including proliferation and cell migration, through activation of multiple signaling molecules in various types of cells. We studied its roles in synovial fibroblasts (SFs) in patients with rheumatoid arthritis (RA) and clarified its relevance to RA synovitis, with the following results. 1)We ...

As is the case with many other peptide hormones of the brain and intestine, the formation of biologically active gastrin from a glycine-extended processing intermediate occurs via the action of a peptidylglycyl alpha-amidating monooxygenase (PAM). The observation that gastrin exists primarily as unamidated precursors in the pituitary but as amidated gastrin in the antrum prompted this study to ...

In this talk I summarize a recently proposed mechanism to understand ππ scattering to 1 GeV. The model is motivated by the 1/NC expansion to QCD, and includes a current algebra contact term and resonant pole exchanges. Chiral symmetry plays an important role in restricting the form of the interactions. The existence of a broad low energy scalar (σ) is indicated.

the omega polynomial(x) was recently proposed by diudea, based on the length of stripsin given graph g. the sadhana polynomial has been defined to evaluate the sadhana index ofa molecular graph. the pi polynomial is another molecular descriptor. in this paper wecompute these three polynomials for some infinite classes of nanostructures.