The lipogenic enzymes fatty acid synthase (FAS; EC 2.3.1.85), citrate cleavage enzyme (CCE; EC 4.1.3.8), malic enzyme (ME; EC 1.1.1.40), glucose-6-phosphate dehydrogenase (G6PDH; EC 1.1.1.49) and 6-phosphogluconate dehydrogenase (PGDH; EC 1.1.1.44) were investigated in liver and in brown adipose tissue (BAT) of Wistar rats under various dietary conditions and in the presence of 15 to 250 ppm (a...

Following unilateral section of the trigeminal third division, the ipsilateral mesencephalic neurons showed severe shrinkage with central chromatolysis and nuclear eccentricity while the motor neurons showed mild swelling. Histochemical reactions in the mesencephalic neurons were mostly characterized by the decreased activity of phosphorylase after 16hrs and concomitant diminution of PAS-positi...

Electrophoretic expression of 20 enzymes coded by a minimum of 30 gene loci is reported for sea lamprey. ADA, ADH. AGP, AAT, CPK, G6PDH, GAPDH, LDH. MDH, PEP, 6PCD, PGI, PGK, PGM, PK, PMI, and SDH yielded gel resolution satisfactory for use in future population studies. Six loci, AGP, !LZDH-1, PGI-I, PGI-2, PGi%f-l, and PlMI were polymorphic. Enzyme expresion did not vary between life stages (a...

Background: Process of oocyte freezing, seriously damages the molecular structure of the oocyte into the life and impair its ability to develop. It seems Oocytes can partially recompense those damages. The pentose phosphate pathway (PPP) constitutes the major source of NADPH required for the neutralization of reactive oxygen species (ROS). Glucose-6-phosphate dehydrogenase (G6PDH) is the first ...

Several links relate mitochondrial metabolism and type 2 diabetes or chronic hyperglycaemia. Among them, ATP synthesis by oxidative phosphorylation and cellular energy metabolism (ATP/ADP ratio), redox status and reactive oxygen species (ROS) production, membrane potential and substrate transport across the mitochondrial membrane are involved at various steps of the very complex network of gluc...

G6PDH is the rate-limiting enzyme of the pentose phosphate pathway and one of the principal source of NADPH, a major cellular reductant. Importantly, in ruminant's metabolism the aforementioned NADPH provided, is utilized for de novo fatty acid synthesis. Previous work of cloning the ovine (Ovis aries) og6pdh gene has revealed the presence of two cDNA transcripts (og6pda and og6pdb), og6pdb bei...

background: diabetes mellitus is considered one of the 5 principal causes of death in the world and is recognized as a global public health issue because of its multifactorial facets affecting essential biochemical processes in the body. this study investigated the antidiabetic and antidyslipidemic activities of the aqueous extract of cochlospermum planchonii (c. planchonii) leaves in streptozo...

Aquaeous methanolic extracts of pomegranate peel (Punica granatum) and veratrum (Veratrum album) were evaluated for their effects supplementation in fish diets on oxidative status, digestive enzymes immunity rainbow trout fingerlings (Oncorhynchus mykiss). Three different concentrations 250 (P250), 500 (P500) 1000 (P1000) mg kg-1 (V250), (V500) (V1000) added to the diet fed these 60 days over a...

Background Diabetes mellitus is considered one of the 5 principal causes of death in the world and is recognized as a global public health issue because of its multifactorial facets affecting essential biochemical processes in the body. This study investigated the antidiabetic and antidyslipidemic activities of the aqueous extract of Cochlospermum planchonii (C. planchonii) leaves in streptozot...