BACKGROUND & OBJECTIVES Most of the non-steroidal anti-inflammatory drugs (NSAIDs) including aspirin cause gastric ulcer. In order to study the gastroprotective effect of Cissus quadrangularis extract (CQE), this study was undertaken on aspirin-induced ulcerogenesis in pyloric ligated (ASP-PL) model in rats. METHODS To assess the possible antiulcer effect of CQE, lesion index, gastric secreti...

BACKGROUND Ethno-botanical information shows that Eremomastax speciosa is used in the traditional management of various stomach complaints including gastro-duodenal ulcers. MATERIALS AND METHODS In this study, we tested the cytoprotective potential of the whole plant methanol extract (100-200 mg/kg, p.o), against HCl/ethanol, absolute ethanol, cold/restraint stress rats, and pylorus legated r...

Bleeding is a complication of gastrointestinal vascular malformation and may be an emergency. Dieulafoy's lesion is rare but the aberrant submucosal artery may cause gastrointestinal bleeding. It is most commonly located in the proximal part of the stomach. Endoscopy is used for diagnosis and treatment. Mass lesions, diffuse lesions and severe bleeding may require surgery. Wedge resection or le...

......................................... Received: 05-10-10 Accepted: 25-11-10 Abstract Although subepithelial lesions are rarely found in the upper gastrointestinal tract, they can cause uncertainty in diagnostic approach and management. Endosonographic findings are described and current recommendations are reviewed in light of one case in order to allow for a rational approach to these lesions.

DOI: 10.1590/S1679-45082017AI3772 A 52-year-old asymptomatic patient underwent a followup endoscopy for Barrett’s esophagus. His exam showed a 1.5cm bulge in the gastric antrum (Figure 1A). The patient was referred for endoscopic ultrasound, which considered the lesion as a gastrointestinal stromal tumor (Figure 1B), but not a typical one, a computed tomography (CT) of the abdomen was, then, su...

A 71-year-old man was referred to us from another hospital for endoscopic treatment of a IIc lesion at the anterior wall of the lower body of the stomach. In November 2008, he underwent resection of this lesion with endoscopic submucosal dissection (ESD). Follow-up endoscopy revealed a IIc lesion in the posterior wall of the lower body of the stomach, and ESD was again performed in February 200...

Gastric adenocarcinoma occurs via a sequence of molecular events known as the Correa's Cascade which often progresses over many years. Gastritis, typically caused by infection with the bacterium H. pylori, is the first step of the cascade that results in gastric cancer; however, not all cases of gastritis progress along this carcinogenic route. Despite recent antibiotic intervention of H. pylor...

The aim of the study was to ascertain the existence of intestinal metaplasia in gastric mucosa of patients with gastric carcinoma coupled with H. pylori positive chronic atrophic gastritis and possible connection of IM with the development of gastric carcinoma. The paper presents prospective study that included 50 patients with gastric carcinoma and 50 patients with chronic atrophic H. pylori p...

INTRODUCTION we report on a case of heterotopic gastric mucosa in the neck of the gallbladder and we also review 95 other reports of HGM in the gallbladder in the international medical literature from 1977. AIM to evaluate the gold standard treatment in heterotopic gastric mucosa of the gallbladder by the analysis of literature, compared with our anecdotal experience. PATIENT AND METHOD a 4...