BACKGROUND/AIMS Available data about reflux patterns and symptom determinants in the gastroesophageal reflux disease (GERD) subtypes off proton pump inhibitor (PPI) therapy are lacking. We aimed to evaluate reflux patterns and determinants of symptom perception in patients with GERD off PPI therapy by impedance-pH monitoring. METHODS We retrospectively reviewed the impedance-pH data in patien...

To determine the relationship between baseline impedance levels and gastroesophageal reflux, we retrospectively enrolled 110 patients (54 men and 56 female; mean age, 51 ± 14 years) with suspected gastroesophageal reflux disease (GERD) who underwent 24-h multichannel intraluminal impedance and pH monitoring. Patients were stratified according to symptom (typical or atypical) and reflux types (a...

Background: Gastroesophageal reflux disease is one of the most common chronic disorders of the digestive system. Almost anyone experiences heartburn or reflux (the two main symptoms of the disease) in a situation. Nutritional changes education as the first step of nursing intervention is the easiest, cheapest and the safest treatment approach. Aim: The aim of this study was to determine the eff...

At the moment, a huge amount of indisputable evidence has been accumulated connection person’s psycho-emotional state with development gastroesophageal reflux disease (GERD). Despite this, there is no single idea exact cause-and-effect relationships that occur when this pathology occurs. In addition, studies problem in children are very few.
 Purpose: to establish features sphere GERD and ...

THE AIM OF THE STUDY Gastroesophageal reflux disease is a common disease with a multifactorial pathogenesis. Our aim was to analyse the role of the Gastroesophageal Disease Questionnaire in diagnosing reflux disease in the population of the Republic of Macedonia. METHODS The questionnaire on the severity of the symptoms related to GERD was used. An evaluation of the distal portion of the oeso...

BACKGROUND Gastroesophageal reflux disease (GERD) is a chronic disease with a negative impact on the quality of life. The aim of this study was to investigate the reflux symptoms and the health-related quality of life in a population with GERD. METHODS Data from patients with GERD, according to the Montreal definition, were collected between January and December 2009. The enrolled patients we...

1Division of Clinical Psychology Public Hospital of Zell am See, Zell am See, Austria 2Department of General Surgery Public Hospital of Zell am See, Zell am See, Austria Although gastroesophageal reflux disease (GERD) can be traced back to disorders of the gastroesophageal junction, stress and other relevant psychological factors can play an important role in the process of GERD. It would seem ...

PURPOSE Gastroesophageal reflux in infant is a physiological process. However, surgery is performed in high risk infants with severe gastroesophageal reflux disease (GERD) when medical management fails. This study focuses on efficacy and safety of Nissen fundoplication for GERD in infants under age 12 months. METHODS This study was a retrospective case analysis of 11 neonates and infants unde...

Background: Type 1 vanilloid receptors (TRPV1) have been described on esophageal afferent sensitive neurons. Stimulation of TRPV1 receptors with capsaicin may induce heartburn. Capsaicin is the pungent component of chili and the most extensively studied TRPV1 agonist. Objectives: To investigate the effect of esophageal stimulation with intraesophageal capsaicin administration on induction of es...

Gastroesophageal reflux disease (GERD) and asthma are both common diseases, and hence they often coexist. However, the prevalence of coexistence of asthma and GERD is far more frequent than by chance association alone. In fact, the relationship between GERD and asthma was firstly described in the 19th century, by Willam Osler: "attacks may be due to direct irritation of the bronchial mucosa or....