Two cases with intractable vomiting due to gastroparesis, a rare feature of diabetic autonomic neuropathy, are described. Both required surgical treatment. In the first a gastroenterostomy was complicated by reflux gastritis requiring a revision operation; in the second a gastrojejunostomy was successful. Electron microscopic studies of the vagus nerve in one of the cases showed a severe reduct...

Review 761 Reasons for Exclusion at Abstract Review Level* No original data: 256 No subjects with suspected gastroparesis or slowtransit constipation: 259 Does not evaluate wireless motility capsule or capsule that measures pH, pressure, motility or transit time: 251 No human subjects: 52 Does not include an adult population: 19 Other reason: 24 Reasons for Exclusion at Article Review Level* No...

Gastroparesis is a condition characterized by delayed gastric emptying and the most common known underlying cause is diabetes mellitus. Symptoms include nausea, vomiting, abdominal fullness, and early satiety, which impact to varying degrees on the patient's quality of life. Symptoms and deficits do not necessarily relate to each other, hence despite significant abnormalities in gastric emptyin...

Gastroparesis is a debilitating disease predominantly affecting young women. Recently, dysregulation of neuronal nitric oxide synthase (nNOS) in myenteric plexus neurons has been implicated for delayed solid gastric emptying/gastroparesis in diabetic patients. In this study, we have explored the role of tetrahydrobiopterin (BH4), a major cofactor for nNOS activity and NO synthesis in diabetic g...

Background: The aim of this study was to evaluate whether patients with increased or decreased gastric motility can be differentiated from healthy volunteers by means of real time magnetic resonance imaging (MRI). Patients and methods: Ten healthy volunteers, 10 patients with gastroparesis, and 10 patients with functional pylorospasm/peptic pyloric stenosis underwent real time MRI. All patients...

Gastroparesis is a rather frequent condition in which the motility of the stomach is extremely delayed or absent, and is usually consequential to many other seemingly unrelated diseases, although rarely idiopathic forms do exist. The disorder is rather common in type 1 diabetes, with a figure of about 10% and is most prevalent in conditions of poor blood glucose control and in developing countr...

BACKGROUND Implantation of a gastric stimulator is a feasible surgical therapy for patients with therapy refractory gastroparesis. In addition it seems to be a promising alternative for treating morbid obesity. We present for the first time the surgical emergency of small bowel obstruction due to strangulation by gastric stimulator electrodes. CASE PRESENTATION A 59-year-old Caucasian female ...