Fluctuation analysis is a method that allows measurement of the single-channel current of ion channels even when it is too small to be resolved directly with the patch-clamp technique. This is the case for voltage-gated calcium channels. They are present in all mammalian central neurons, controlling presynaptic release of transmitter, postsynaptic signaling, and synaptic integration. The amplit...

Abstract Electrolyte-gated transistors can function as switching elements, artificial synapses and memristive systems, could be used to create compact powerful neuromorphic computing networks. However, insight into the underlying physics of such devices, including complex ion dynamics resulting capacitances, remains limited. Here we report a concise model for transient ion-dynamic capacitance i...

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