PURPOSE To compare the diagnostic accuracy of scanning laser polarimetry (SLP) parameters between images taken with enhanced corneal compensation (ECC) and those with variable corneal compensation (VCC) and to explore the effect of atypical birefringence patterns on this accuracy. DESIGN Cross-sectional observational study. PARTICIPANTS Forty-one healthy subjects and 92 patients with primar...

normal 0 false false false en-us x-none ar-sa background: this study was designed to investigate the effect of vitiligo on the retinal nerve fiber layer (rnfl) thickness. materials and methods: this prospective study was conducted in the department of ophthalmology at kä±rä±kkale university during 2010 and 2011.sixty eight eyes of 34 vitiligo patients were included in the study. eighty four eye...

To reveal direct effects of androgens, independent of glucocorticoids, we studied the effects of gonadectomy (GDX) in adrenalectomized (ADX) rats with or without androgen replacement on corticotropin releasing hormone (CRH) and arginine vasopressin (AVP) mRNA expression within various forebrain sites known to regulate the hypothalamic-pituitary-adrenal axis. These included the medial parvocellu...

OBJECTIVE To analyze the benefit of voiding chain cystourethrography (VCC) [placing a radiographic opaque chain into the urethra and bladder and asking the patient to void under fluoroscopy] in the urodynamic evaluation of female bladder outlet obstruction (BOO). MATERIALS AND METHODS Females with post anti-incontinence operation voiding dysfunction who underwent urodynamic evaluation augment...

PURPOSE To investigate whether correction for atypical birefringence pattern (ABP) using scanning laser polarimetry with enhanced corneal compensation (SLP-ECC) reduces the severity of ABP compared with variable corneal compensation (SLP-VCC) and improves the correlation with visual function. DESIGN Prospective observational study. METHODS Normal and glaucomatous eyes enrolled from four cli...

Vehicular cloud computing (VCC) system coordinates the vehicular cloud (consisting of vehicles’ computing resources) and the remote cloud properly to provide in-time services to users. Although pervious works had established the models for resource allocation in the VCC system based on semiMarkov decision processes (SMDP), few of them discussed heterogeneity of vehicles and influences of roadsi...

Normal age-related testosterone depletion in men is a recently identified risk factor for Alzheimer's disease (AD), but how androgen loss affects the development of AD is unclear. To investigate the relationship between androgen depletion and AD, we compared how androgen status affects the progression of neuropathology in the triple transgenic mouse model of AD (3xTg-AD). Adult male 3xTg-AD mic...

Gonadectomy (GDX) induces sex steroid-producing adrenocortical tumors in certain mouse strains and in the domestic ferret. Transcriptome analysis and DNA methylation mapping were used to identify novel genetic and epigenetic markers of GDX-induced adrenocortical neoplasia in female DBA/2J mice. Markers were validated using a combination of laser capture microdissection, quantitative RT-PCR, in ...

Vibrio cholerae cytolysin/hemolysin (VCC) is a 65 kDa β-pore-forming toxin causing lysis and death of eukaryotic cells. Apart from the core cytolysin domain, VCC has two lectin domains with β-trefoil and β-prism folds. The β-prism domain binds to cell surface carbohydrate receptors; the role of the β-trefoil domain is unknown. Here, we show that the pro-VCC mutant without the β-trefoil domain f...