نتایج جستجو برای: gemfibrozil

تعداد نتایج: 550  

Journal: :Proceedings of the Royal Society of Medicine 1976

Journal: :Chemical communications 2001
A I Khan L Lei A J Norquist D O'Hare

A series of pharmaceutically active compounds including diclofenac, gemfibrozil, ibuprofen, naproxen, 2-propylpentanoic acid, 4-biphenylacetic acid and tolfenamic acid can be reversibly intercalated into a layered double hydroxide, initial studies suggest that these materials may have application as the basis of a novel tuneable drug delivery system.

Journal: :Medicine & Science in Sports & Exercise 2019

Journal: :General physiology and biophysics 2009
Danijela Ristic-Medic Slavica Suzic Vesna Vucic Marija Takic Jasna Tepsic Marija Glibetic

Hyperlipidemia is found to be associated with changes in fatty acid (FA) profiles. The aim of this study was to investigate the effects of AHA-Step-1 dietary treatment and combination of fibrates (gemfibrozil) with dietary intervention on serum and erythrocyte phospholipid FA composition in human hyperlipidemia. 78 study participants with hyperlipidemia were divided in two groups. In D group (n...

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2009
Peter J Kilford Rowan Stringer Bindi Sohal J Brian Houston Aleksandra Galetin

Glucuronidation via UDP-glucuronosyltransferase (UGT) is an increasingly important clearance pathway. In this study intrinsic clearance (CL(int)) values for buprenorphine, carvedilol, codeine, diclofenac, gemfibrozil, ketoprofen, midazolam, naloxone, raloxifene, and zidovudine were determined in pooled human liver microsomes using the substrate depletion approach. The in vitro clearance data in...

Journal: :Journal of hepatology 2015
Rajeev M Menon Prajakta S Badri Tianli Wang Akshanth R Polepally Jiuhong Zha Amit Khatri Haoyu Wang Beibei Hu Eoin P Coakley Thomas J Podsadecki Walid M Awni Sandeep Dutta

BACKGROUND & AIMS Paritaprevir (administered with ritonavir, PTV/r), ombitasvir (OBV), and dasabuvir (DSV) are direct-acting antiviral agents (DAAs) for the treatment of chronic hepatitis C virus (HCV) infection. Thirteen studies were conducted to characterize drug-drug interactions for the 3D regimen of OBV, PTV/r, and DSV and various medications in healthy volunteers to inform dosing recommen...

H Khalili Kh Gholami R Ramezani S Dashti

Introduction: Hyperlipidemia is one of the most important and common risk factors of cardiovascular diseases especially Atherosclerosis and consequently CHD. Unalike age and gender, hyperlipidemia is a factor which can be controlled by altering the life style, nutritional habits and medical-medicinal interventions. Although serum level of cholesterol is always noticed in hyperlipidemia, hypertr...

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