نتایج جستجو برای: gene expression signature

تعداد نتایج: 1655967  

2014
Jin Meng Ping Li Qing Zhang Zhangru Yang Shen Fu

BACKGROUND Many long non-coding RNAs(lncRNAs) have been found to be a good marker for several tumors. Using lncRNA-mining approach, we aimed to identify lncRNA expression signature that can predict breast cancer patient survival. METHODS We performed LncRNA expression profiling in 887 breast cancer patients from Gene Expression Omnibus (GEO) datasets. The association between lncRNA signature ...

2017
Peng Song Bo Jiang Zhijian Liu Jie Ding Song Liu Wenxian Guan

Long noncoding RNAs (lncRNAs) have emerged as essential players in gene regulation. An ever-increasing number of lncRNAs has been found to be associated with the biogenesis and prognosis of gastric cancer (GC). We aimed to develop an lncRNA signature with prognostic value for survival outcomes of GC. Using an lncRNA mining approach, we analyzed the lncRNA expression profiles of 492 GC patients ...

2014
Baohua Wang Ning Song Tong Yu Lianya Zhou Helin Zhang Lin Duan Wenshu He Yihua Zhu Yunfei Bai Miao Zhu

In this study, we conducted a meta-analysis on high-throughput gene expression data to identify TNF-α-mediated genes implicated in lung cancer. We first investigated the gene expression profiles of two independent TNF-α/TNFR KO murine models. The EGF receptor signaling pathway was the top pathway associated with genes mediated by TNF-α. After matching the TNF-α-mediated mouse genes to their hum...

Journal: :Arteriosclerosis, Thrombosis, and Vascular Biology 2021

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