Molecular genetics selection on individual genes is a promising method to genetically improve economically important traits in livestock. The insulin like growth factor-I (IGF-I) gene may play important roles in growth of multiple tissues, including muscle cells, cartilage and bone. The objectives of the present study were the estimate the haplotype frequencies of the IGF-I gene polymorphisms i...

Gene expression data are usually known for having a large number of features. Usually, some these features irrelevant and redundant. However, in cases, all features, despite being numerous, show high importance contribute to the analysis. In similar fashion, gene sometimes have limited instances with rate imbalance among classes. This can limit exposure classification model different categories...

seedlessness is the most important trait in table grape and raisin industry which has attracted breeders from long ago. breeding grapes by traditional methods result in low number of seedless progenies and their selection requires long time. therefore, marker-assisted selection (mas) can overcome the selection difficulty and would decrease high cost of progeny maintenance for several years. in ...

Switching on a gene typically involves either a transcription factor that binds to stimulate transcription, or a repressor that releases to allow transcription. In both cases, the regulatory protein responds to an external biochemical signal. Control theory assigns the label ‘‘doublepositive’’ ( ), to the regulation mode in which the signal activates a factor that activates the gene, and ‘‘doub...

MOTIVATION An important step in analyzing expression profiles from microarray data is to identify genes that can discriminate between distinct classes of samples. Many statistical approaches for assigning significance values to genes have been developed. The Comparative Marker Selection suite consists of three modules that allow users to apply and compare different methods of computing signific...

Changes in genetic regulation contribute to adaptations in natural populations and influence susceptibility to human diseases. Despite their potential phenotypic importance, the selective pressures acting on regulatory processes in general and gene expression levels in particular are largely unknown. Studies in model organisms suggest that the expression levels of most genes evolve under stabil...

biochemical polymorphism study is a method of determination of genetic variation. this variability could be a basis for selection and subsequent genetic improvement in farm animals. the polymorphism in the intron 1 of chicken growth hormone (cgh) gene was investigated in the iranian native fowls by using polymerase chain reaction (pcr)-restriction fragment length polymorphism (rflp) method. the...