Colorectal cancer is the third most common malignancy worldwide. It also fourth leading cause of death among all malignant tumours. The treatment modalities for colorectal include surgery, chemotherapy, radiotherapy, biotargeted therapy, gene therapy and biological immunotherapy [1,2].

EDITORIAL article Front. Med., 08 August 2023Sec. Gene and Cell Therapy Volume 10 - 2023 | https://doi.org/10.3389/fmed.2023.1225551

We review several recent advancements of peptide-based nanomaterials and highlight their important roles in the application gene therapy.

In its purest form, gene therapy is the delivery and expression of a correct copy of a gene into cells in which the endogenous gene is nonfunctional. It can lead to cure — or significant enhancement of the quality of life — of the patient. The concept is highly attractive as it provides a therapeutic link between laboratory-based studies on the genetic basis of disease and attempts to alleviate...