We introduce the sequence of generalized Gončarov polynomials, which is a basis for the solutions to the Gončarov interpolation problem with respect to a delta operator. Explicitly, a generalized Gončarov basis is a sequence (tn(x))n≥0 of polynomials defined by the biorthogonality relation εzi(d (tn(x))) = n!δi,n for all i, n ∈ N, where d is a delta operator, Z = (zi)i≥0 a sequence of scalars, ...