background: muslim women tend to postpone their menstrual period using short course oral contraceptives (oc) during ramadan, muslims fasting month. recently, many cases of stroke, particularly cerebral vein thrombosis (cvt), have been reported in ramadan. objective: this work studies the incidence of cvt and its relation to ramadan. materials and methods: this is a cohort study conducted from o...

background: we report a case series of cerebral vein thrombosis (cvt) in women who used oral contraceptive pill (ocp) in the muslims ramadan and fasting month. methods: this study was a retrospective case series of 9 patients with diagnosis of cvt, who admitted in the neurology ward of tohid hospital of sanandaj, iran, in july-august 2014-2015. results: patients had no history of thrombosis bef...

BACKGROUND The aim of this study was to determine if oral contraceptive (OC) use affects body weight, body composition and metabolism in primates. METHODS Reproductive-age female rhesus monkeys of normal and obese BMI were studied to document baseline weight stability, then treated continuously with an OC (dosed to achieve equivalent human serum levels for a 30 µg ethinyl estradiol/150 µg lev...

Single-point mutations in the gene coding for prothrombin (factor II:A20210) or factor V (factor V:A1691) are associated with an increased risk of venous thromboembolism. The use of oral contraceptives is also a strong and independent risk factor for the disease, and the interaction between factor V:A1691 and oral contraceptives greatly increases the risk. No information is available about the ...

OBJECTIVE To explore the usefulness of epidemiological data to guide clinical practice by seeking an answer to the question "What is the risk of cardiovascular disease among users of currently available, low dose, combined oral contraceptives who are aged less than 35 years, do not smoke, and do not have a medical condition known to increase the risk of vascular disease?" DESIGN Review of all...

introduction: oral contraceptives (ocs) are considered as one of the most common risk factor of venous thromboembolism (vte) in child bearing age. some of the recent researches indicate that the odds of vte may be even higher with newer generations of ocs. the present meta-analysis was designed to evaluate the effect of different generation of ocs on the occurrence of vte. methods: two research...

Background and objectives: Hypericum perforatum L., commonly known as St. John’s wort (SJW) from the family Hypericaceae is a famous medicinal plant used to treat mild to moderate depression; so, it might affect the pharmacokinetics of numerous drugs. Due to widespread herb-drug interactions of SJW, this study was designed to review the clinical evidences regarding the...

OBJECTIVE To estimate whether daily educational text messages affect oral contraceptive pill (OCP) continuation at 6 months. METHODS We randomized young women electing OCPs at an urban family planning health center to either routine care or routine care plus 180 days of daily educational text messages. Investigators masked to treatment allocation randomized participants who were not masked to...

OBJECTIVE To examine the economic impact of a new implantable contraceptive, Implanon, in comparison with other available contraceptive methods. DESIGN This was a modelling study using cost data derived from national published sources and effectiveness data from either controlled clinical trials (Implanon) or reports in the literature (other contraceptives). In the baseline analysis, Implanon...