BACKGROUND Inflammatory bowel disease (IBD) is a chronic disease of unknown etiology, in which genetic factors, seem to play an important role in the disease predisposition and course. Assessment of tumor necrosis factor (TNF-α) gene polymorphisms in many populations showed a possible association with IBD. Considering the genetic variety in different ethnic groups, the aim of the present study ...

The agricultural transition profoundly changed human societies. We sequenced and analysed the first genome (1.39x) of an early Neolithic woman from Ganj Dareh, in the Zagros Mountains of Iran, a site with early evidence for an economy based on goat herding, ca. 10,000 BP. We show that Western Iran was inhabited by a population genetically most similar to hunter-gatherers from the Caucasus, but ...

The evolution of building codes typically produce design provisions that are expected to create safer and more accurate designs. We as engineers expect building codes to advance the state of the art with each successive edition. The 2009 International Building Code (IBC) and the Building Code Requirements for Structural Concrete (ACI 318-08) have significant revisions affecting the design of ti...

Iran is one of the most important mohair-producing countries in the world. Markhoz goat is the only breed producing mohair in Iran that is showing endangerment trend in its native breeding region. The aim of this study was to evaluate the genetic diversity of Markhoz goat and its color types using ISSR markers. Four primers were designed and two of them were selected based on their number of ba...

BACKGROUND Leishmaniasis is important vector-borne parasitic disease worldwide, caused by the genus Leishmania. The objective of the current study was to identify genetic polymorphism in L. major, one of the species causing cutaneous leishmaniasis (CL), isolated from southeastern Iran, using Permissively Primed Intergenic Polymorphic-Polymerase Chain Reaction (PPIP-PCR) method. METHODS Overal...

INTRODUCTION Physicians have to visit, diagnose and refer patients with genetic disorders, so they need to be familiar with the basics and indications of genetic tests. In other words, they should have effective theoretical and practical knowledge about medical genetics before they do their job. Medical genetics courses at Medical Universities of Iran are generally presented as a theoretical su...

The objective of present study was identification of genetic similarity between wild Iran and captive Azerbaijan Pheasant using PCR-RAPD markers. For this purpose, in overall, 28 birds were taken for DNA extraction and subsequently 15 arbitrary primers were applied for PCR-RAPD technique. After electrophoresis, five primers exhibited sufficient variability which yielded overall 65 distinct band...

Abstract Recently, there has been a development in transgenic technologies many countries to meet nutritional needs of increasing worlds? population. However, are some concerns about possible risks the field growing genetically modified (GM) food, such as threats biodiversity and food allergies making their use challenge. Therefore, present study was conducted investigate economic effects polit...

This is the first genetic biodiversity study of Mycobacterium tuberculosis in Iran. Thus, we investigated the genetic patterns of strains isolated in the first survey of anti-tuberculosis drug-resistance by rpoB gene as part of the Global Project of Anti-tuberculosis Drug Resistance Surveillance (IAU, Iran). A 411-bp fragment of the rpoB gene, containing the sequence of the 81-bp rpoB fragment,...