نتایج جستجو برای: genetic linkage
تعداد نتایج: 641476 فیلتر نتایج به سال:
The inherited genetic defect in adenomatous polyposis has been localized to a small region on the long arm of chromosome 5. Sixteen DNA marker loci were used to construct a linkage map ofthe chromosome. When five kindreds segregating a gene for adenomatous polyposis coli were characterized with a number of the markers, significant linkage was found between one marker and the disease gene. Linka...
BACKGROUND Familial aggregation and segregation analysis studies have provided evidence of a genetic basis for esophageal adenocarcinoma (EAC) and its premalignant precursor, Barrett's esophagus (BE). We aim to demonstrate the utility of linkage analysis to identify the genomic regions that might contain the genetic variants that predispose individuals to this complex trait (BE and EAC). METH...
Linkage identification algorithms identify linkage groups — sets of loci tightly linked — before genetic optimizations for their recombination operators to work effectively and reliably. This paper proposes a parallel genetic algorithm (GA) based on the linkage identification algorithm and shows its effectiveness compared with other conventional parallel GAs such as master-slave and island mode...
Vertebrate sensory systems have evolved remarkable diversity, but little is known about the underlying genetic mechanisms. The lateral line sensory system of aquatic vertebrates is a promising model for genetic investigations of sensory evolution because there is extensive variation within and between species, and this variation is easily quantified. In the present study, we compare the lateral...
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