In this study we showed TLR2 CpG promoter methylation in periodontitis affected human gingival tissues and in primary human gingival epithelial cells chronically stimulated with P. gingivalis that may instigate epithelial dysbiosis that may create a unique pathogen niche in the gingival crevice and susceptibility to periodontitis.

abstract background: although cyclosporine (csa) and calcium channel blockers (ccbs) parallel to each other may provoke gingival enlargement (ge), there are few considerations about combined effects of csa and ccbs on gingival tissues. objectives: this study aimed to determine prevalence of ge among renal transplant recipients and to compare its occurrence in patients who received only csa and ...

BACKGROUND AND OBJECTIVE The subepithelial connective tissue graft (SCTG) is the most widely used procedure for the treatment of gingival recession defects. Little is known, however, as to whether the apposed gingival flaps are more predisposed to develop plaque-related inflammation compared to healthy sites. This has salient clinical implications, as the long-term results of root coverage will...

Melanin pigmentation of the gingiva is a common occurrence. Depending on the gingival display during smiling, corrective measures may be needed for an esthetic purpose. Diode laser is a minimally invasive treatment option for the treatment of gingival melanin pigmentation. Three case reports of gingival depigmentation procedure performed using a 980 nm diode laser are presented here.

background: gingival recession is the most common and undesirable condition of the gingiva. the aim of study was to investigate the aetiology and severity of gingival recession in a greek adult population sample.     methods: the study was performed on 165 males and 179 females, 18-68 years old who sought dental treatment in a private dental practice and showed gingival recession. all subjects ...

Background: Cigarette smoking is a significant risk factor for periodontal disease. It also causes pigmentation of oral mucosa. The present study was aimed to assess the effects of smoking on lip and gingival pigmentation and periodontal status and the relationship between pigmentation and periodontal parameters. Methods: A total of 109 smokers and an equal number of non-smoker controls (mean a...

Human beta-defensin-1 (hBD-1) is a member of the family of small cationic antimicrobial peptides that have been identified in several mucosal epithelia. Because human gingival epithelium is a site that is constantly challenged by oral microorganisms, we examined the expression of hBD-1 in human gingival epithelial and fibroblast cell cultures and tissue samples. Cell cultures were challenged wi...

AIM This study aimed to evaluate the microleakage of Class V restorations filled with a 7th-generation self-adhesive composite. MATERIALS AND METHODS In 40 permanent premolars and 80 primary canines, 160 Class V cavities were prepared, which were filled with four restorative materials (n of each material=20 permanent and 20 primary restorations): control: nonbonded composite (Heliomolar), GI:...

Gingival recession is commonly associated with plaque‐induced inflammation and calculus. A high frenal attachment is more important in gingival recession in the child‐patient. A healthy child‐patient with impeccable oral hygiene presented with localized gingival recession without plaque‐induced inflammation which led to the exploration of other possible etiologies. Multiple factors appeared to ...