Gingival overgrowth is a common adverse effect of therapy with Phenytoin, having important medical and cosmetic implications. Poor periodontal hygiene is an important risk factor for severity of Phenytoin-induced gingival overgrowth (PIGO), which is a time-dependent process. There is complex interplay of altered fibroblast biology, connective tissue turnover, inflammatory processes, and growth ...

OBJECTIVES This study was undertaken to investigate the OPG profiles in gingival crevicular fluid (GCF), saliva, and gingival tissues of chronic periodontitis (CP) patients in response to open flap debridement (OFD). SUBJECTS AND METHODS The study included 30 subjects divided into 2 groups: 20 CP patients and 10 periodontally healthy subjects. Plaque index, gingival index, pocket depth, and c...

one of the most commonly used procedures in contemporary periodontics. Indications include: (1) lack of sufficient length of a clinical crown to ensure a tooth preparation for fixed prosthodontics with retentive and resistance form; (2) preexisting dental caries or restorations in the vicinity of the free gingival margins that prevent preparation of finish lines for restorative margins coronal ...

Bleaching agents can potentially cause damage to dental and gingival tissues. Due to the use of bleaching agents close to gingival tissues, the objective of the present study was to test the hypothesis that the higher the concentration of hydrogen peroxide, the greater is the cytotoxicity to fibroblast cells. Two concentrations of hydrogen peroxide (6%, and 7.5%) used in home bleaching techniqu...

Amaç: Yeni nesil metal desteksiz dental seramiklerin uzun süreli biyouyumluluğu ile ilgili olarak oldukça az bilgi mevcuttur. Bu çalışmanın amacı, farklı dental seramiklerin gingival fibroblast canlılığına olan etkisini değerlendirmektir. Gereç ve Yöntem: İnsan gingival fibroblastı, 2 farklı feldspathic seramiğe (Vita Omega ve Ivoclar), bir lithium disilicate preslenebilir seramiğe (Empress-2) ...

Periodontal diseases, which are inflammatory diseases of bacterial origin affecting the tooth-supporting tissues, are characterized by inflammation and destruction of gingival connective tissue and alveolar bone, and may lead to tooth loss. The aim of the study was to investigate Rokumigan, a Kampo Japanese traditional medicine made of six different plants, for its capacity to prevent biofilm f...

AIM This article describes the surgical management of a young, female patient with severe gingival enlargement of unknown etiology. BACKGROUND Gingival enlargement frequently occurs as gingival hyperplasia, representing a reaction to a known stimulus or agent and, histopathologically, implies an increase in both extracellular matrix and cell numbers. The enlargement may range from mild, in wh...