Although gastrointestinal stromal tumor (GIST) is one of the most commonly seen mesenchymal system, it's rare in appendix. Incidental sessile serrated lesions (SSLs) which are during colonoscopy also In our patient who was operated with a diagnosis acute appendicitis, we detected an incidental GIST and accompanying SSL. Up to date, coincidence these 2 entities same case hasn't been reported lit...

AIM To evaluate the efficacy of doubling time (DT) of gastrointestinal submucosal tumors (GIST). METHODS From April 1987 through November 2012, a total of 323 patients were given a final histopathological diagnosis of GISTs on surgical resection or endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in Kitasato University East Hospital or Kitasato University Hospital. We studied 53 ...

Background About 80% patients with GIST would experience tumor recurrence or metastases after a prior radical resection. The most common metastatic site is liver. Imatinib mesylate was proved to be effective for advanced GIST. Current study was designed to observe the influence of liver metastases to the outcome of imatinib treatment for recurrent GIST from prior surgery. Methods 42 patients ha...

Gastrointestinal stromal tumor (GIST) is the most major mesenchymal neoplasm of the digestive tract. Up to now, imatinib mesylate has been used as a standard first-line treatment for irresectable and metastasized GIST patients or adjuvant treatment for advanced GIST patients who received surgical resection. However, secondary resistance to imatinib usually happens, resulting in a major obstacle...

We present a case of small bowel diverticulum with gastrointestinal stromal tumor (GIST). This GIST in the diverticulum was confirmed by immunohistochemistry and was of low-grade malignant potential.

Gastrointestinal stromal tumor (GIST) is the most common sarcoma, often resulting from a KIT or platelet-derived growth factor receptor alpha (PDGFRA) mutation. The lineage transcription factor ETV1 is expressed similarly in GISTs regardless of malignant potential. Although the related transcription factor ETV4 has been associated with metastasis and tumor progression in other cancers, its role...

A 69-year-old man was admitted with a large elastic mass in the upper abdomen. Computed tomography revealed a massive tumor in contact with the liver and gastrointestinal endoscopy revealed a gastric adenocarcinoma. He developed acute renal failure with massive proteinuria and died with a marked enlargement of the tumor. Autopsy revealed a tumor located in the lesser omentum. The tumor was cons...

Compared to gastric gastrointestinal stromal tumor (GIST), hepatic GIST is very rare in clinic. Reports on clinicopathological feature and prognosis of this rare disease are limited in literature. The purpose of this study was, therefore, to summarize clinical and pathological features as well as prognosis of the primary hepatic GIST. One case of primary hepatic GIST from our center and 22 case...

Tailgut cysts and rectal gastrointestinal stromal tumors (GIST) are rare found in the retrorectal space. congenital malformations resulting from incomplete regression of hindgut during embryogenesis they mostly affect women third to sixth decade life; GIST account for 5% all GIST. Both conditions may present with nonspecific symptoms such as pelvic or anal pain, bleeding weight loss. usually be...

BACKGROUND We sought to investigate the characteristics and survival rate of patients with gastrointestinal stromal tumor (GIST) associated with other primary malignancies. PATIENTS AND METHODS A total of 783 patients with GIST were identified from 1995 to 2007. Additional primaries included tumors not considered metastasis, invasion, or recurrence of GIST, nor non-melanoma skin cancer. Data ...