In dogs, meningiomas and gliomas appear to occur most frequently. Most primary brain tumors are solitary, but multiple primary brain tumors have been reported. Secondary or metastatic tumors appear to be less common and may result from local extension (e.g. nasal adenocarcinoma) or metastases from primary tumors elsewhere. Skull tumors may affect the brain by local extension. Although brain tum...

PURPOSE To evaluate the clinical characteristics, management approaches and life expectancy in pediatric patients with neuroepithelial glial tumors except ependymal tumors. METHODS Between January 2003 and August 2008, 48 patients (30 boys, 18 girls; mean age: 10.9 ± 4.6 years) who were diagnosed with neuroepithelial glial tumors except ependymal tumors and underwent curative radiotherapy (RT...

Central nervous system neoplasms include diverse group of tumors with a wide spectrum of morphologies, tissues of origin, histologic subtypes and molecular abnormalities. Despite their relatively rare occurrences, these tumors can result in considerable mortality as well as morbidity. Depending on their tissue of origin, these neoplasms can be broadly divided into glial and non-glial tumors. Pr...

OBJECTIVES To evaluate whether polymorphisms in the deoxy-ribonucleic acid (DNA) repair genes XRCC1 and XPD, have efficacy in the development of brain tumors. METHODS This is a case-population based study, including 135 cases of brain tumors, and 87 population based age- and gender-matched healthy controls. We examined the role of XRCC1 Arg 399Gln gene and XPD Lys751Gln gene polymorphisms, in...

Nasal glial heterotopia (nasal glioma) is the term used to describe a mass made up of mature brain tissue that is isolated from the cranial cavity or spinal canal. Most of these rare, benign, congenital tumors are found in the nasal region, particularly at the bridge of the nose and in the nasal cavity. Nasal glial heterotopia is frequently diagnosed in newborns; a few cases have been found in ...

Brain tumor growth or progression has been shown to occur in low-grade glial tumors and meningiomas. While progression has been documented in this population, transformation to a more aggressive high-grade glial tumor that can lead to increased morbidity and mortality has not been identified. In this case series, we document transformation from low-grade gliomas to highgrade gliomas (WHO grade ...