This study compared the interfacial and emulsifying properties of purified saponins non-purified saponin-rich extracts Glycyrrhiza glabra, highlighted potential mechanisms by which crude surface-active compositions, such as liquorice root extract (LRE), act emulsifiers. LRE presented different fluid properties, in comparison to glycyrrhizin (PG), at equivalent concentrations. Particularly, it e...

Hepatoprotectors – drugs that form the basis of pathogenetic treatment various liver diseases. They help restore impaired hepatocyte function, increase resistance cells to effects pathological factors, enhance detoxification function hepatocytes, have antioxidant properties. There is no generally accepted classification hepatoprotectors today, they are divided into several groups depending on o...

In vivo and in vitro sublethal exposure of abrin, glycyrrhizin (active component of Abrus precatorius seed and root), sanguinarine, protopine (Argemone mexicana seed) and oleandrin (Nerium indicum leaf) inhibited the acetylcholinesterase, lactic dehydrogenase, acid and alkaline phosphatase activity in the nervous tissue of Lymnaea acuminata. The succinic dehydrogenase activity in the nervous ti...

A prospective study was carried out on 12 patients with chronic hepatitis who were taking 546 mg/day of glycyrrhizin for 4 weeks in order to identify the factors responsible for the development of hypertension and hypokalemia. In 5 patients, blood pressure increased and serum potassium decreased after the treatment (responders). In the remaining 7 patients, these values were unchanged (nonrespo...

Liquorice has an active substance, Glycyrrhizin which inhibits the conversion of precursor cortisol to cortisone by inhibiting the enzyme 11-betahydroxysteroid dehydrogenase. When imbibed, liquorice acts like hyperaldosteronism which presents with typical symptoms including high blood pressure, low blood potassium, and muscle pain and weakness. This article appraises physiological and pharmacol...